anti-Daxx Antibody
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Catalog number1163
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoDaxx Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
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Gene namesDaxx Antibody: DAP6, EAP1, BING2, DAP6, Death domain-associated protein 6, Daxx, hDaxx
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Antibodie s labelunlabelled serum
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PurityDaxx Antibody is Antibody is DEAE purified.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenDaxx antibody was made against a peptide corresponding to amino acids near the carboxy terminus of human Daxx.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry
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Antibody adviceDaxx antibody can be used for detection of Daxx by Western blot at 1 ug/mL. A 120 kDa major band can be detected. Antibody can also be used for immunocytochemistry starting at 10 ug/mL.
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Suspention pH azideDaxx Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atDaxx antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse
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Omim nr48146287
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Ncbi nrCAG33366
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KDa120 kDa
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Vial with antibodyin solution
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NCBI GENE nr1616
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GENE symbolDAXX
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Antigene namedeath-domain associated protein
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SourceHomo sapiens
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Protein nrQ9UER7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDAXX
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Short nameanti-Daxx Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toDaxx (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetdeath-domain associated protein, BING2 and DAP6 and EAP1, DAXX and IDBG-82726 and ENSG00000204209 and 102723452,1616, androgen receptor binding, nuclei, Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163, DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336
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Gene info
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Identity
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Gene
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Long gene namedeath domain associated protein
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Synonyms gene name
- death-associated protein 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-03-25
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data