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anti-CIDE-C Antibody

  • Catalog number
    6968-100
  • Product name
    anti-CIDE-C Antibody
  • Size
    CIDE-C Antibody
  • Price
    338EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human
  • Purification method:
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Immunogene sequence:
    This CIDEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human CIDEC
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    CIDE-C
  • Formulation of this antibody:
    In PBS with 0.09% (W/V) sodium azide
  • Alternative names of antibody target:
    Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC, FSP27
  • Recommended usage:
    WB: ~1:1000
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit Ig
  • Background information:
    CIDEC binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-CIDE-C Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-CIDE-C (Antibody to)
  • Alternative technique
    antibodies
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