CD105/Endoglin Antibody (Center E395)

• Catalog number
  6800-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  CD105
• Target Alternative Name
  ENG; END; Endoglin
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse.
• Immunogen Sequence
  This CD105 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human CD105.
• Accession
  P17813
• Gene Id
  2022
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.09% (W/V) sodium azide.
• Purification
  Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
• Application
  Western blot, IHC, FACS.
• Positive Control
  Western blot: Mouse heart tissue lysate, IHC: mouse heart tissue, FACS: NCI-H292.
• Application And Usages
  WB: 1:1000, IHC: 1:10 – 1:50, FC: 1:10 – 1:50.
• Description
  Endoglin (ENG, CD105) is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways. Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos. Mutations in endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure. The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD105/Endoglin   Center   E395  
• Gene symbol
  ENG
• Short name
  CD105/Endoglin Antibody (Center E395)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  CD105/Endoglin (antibody to-) (central E395)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3349
• Gene
  ENG
• Long gene name
  endoglin
• Synonyms gene
  • ORW1
  • ORW
• Synonyms gene name
  • Osler-Rendu-Weber syndrome 1
• Synonyms
  • END
  • HHT1
  • CD105
• GenBank acession
  • AF035753
• Locus
  9q34.11
• Discovery year
  1993-03-03
• Entrez gene record
  2022
• Pubmed identfication
  • 8404038
  • 10548503
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000020723
• Locus Specific Databases
  • Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database
  • LRG_589

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products