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anti-ALDH2 Antibody (NT)

  • Catalog number
    6749-100
  • Product name
    anti-ALDH2 Antibody (NT)
  • Size
    ALDH2 Antibody (NT)
  • Price
    316EUR
  • Supplier
    biovision antibodies-kits-proteins
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  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human mouse and rat.
  • Purification method:
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Immunogene sequence:
    This ALDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human ALDH2.
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, IF.
  • Target of this antibody:
    ALDH2
  • Formulation of this antibody:
    100 µl of antibody in PBS with 0.09% (W/V) sodium azide
  • Alternative names of antibody target:
    ALDH2; ALDM; Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI.
  • Recommended usage:
    Western blot: ~1:1000, IF: ~1:10-1:50.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Clone:
    N/A
  • Background information:
    ALDH2 (Aldehyde dehydrogenase 2 family) belongs to the aldehyde dehydrogenase family which catalyze the chemical transformation from acetaldehyde to acetic acid and is the second enzyme of the major oxidative pathway of alcohol metabolism. Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase cytosolic; ALDHII; ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). The major liver isoform ALDH1 localizes to cytosolic space, while ALDH2 localizes to the mitochondria. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH2 is present in most Caucasians, yet is absent in 50% of Asians. The absence of this enzyme has been linked to alcohol intolerance; and thusly, a reduced risk for alcoholism-related liver disease.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-ALDH2 Antibody (NT)
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-aldehyde dehydrogenase 2 family (mitochondrial) (Antibody to) (NT)
  • Alternative technique
    antibodies
  • Alternative to gene target
    aldehyde dehydrogenase 2 family (mitochondrial), ALDH-E2 and ALDHI and ALDM, ALDH2 and IDBG-57710 and ENSG00000111275 and 217, this GO :0004029 and aldehyde dehydrogenase (NAD) activity and molecular function this GO :0004030 and aldehyde dehydrogenase [NAD(P)+] activity and molecular function this GO :0005759 and mitochondrial matrix and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006066 and alcohol metabolic process and biological process this GO :0006068 and ethanol catabolic process and biological process this GO :0006069 and ethanol oxidation and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0007268 and synaptic transmission and biological process this GO :0008152 and metabolic process and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0042136 and neurotransmitter biosynthetic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, oxidoreductase activity, this GO :0004029: aldehyde dehydrogenase (NAD) activity and also this GO :0004030: aldehyde dehydrogenase [NAD(P)+] activity and also this GO :0009055: electron carrier activity and also this GO :0016491: oxidoreductase activity, this GO :0004029: aldehyde dehydrogenase (NAD) activity, this GO :0004030: aldehyde dehydrogenase [NAD(P)+] activity, this GO :0009055: electron carrier activity, this GO :0016491: oxidoreductase activity, multiple
  • Ask
1. Gene info
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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