anti-ADAM10 Antibody

• Catalog number
  2051
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  ADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-a;) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a;, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a;, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
• Gene names
  ADAM10 Antibody: RAK, kuz, AD10, AD18, MADM, CD156c, HsT18717, KUZ, Disintegrin and metalloproteinase domain-containing protein 10, CDw156, ADAM 10
• Antibodie s label
  unlabelled serum
• Purity
  ADAM10 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  ADAM10 antibody was made against a 17 amino acid peptide near the carboxy terminus of human ADAM10.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
• Antibody advice
  ADAM10 can be used for detection of ADAM10 by Western blot at 1 - 2 ug/mL. This polyclonal antibody can also detect ADAM10 by immunohistochemistry at 2 ug/mL. For immunofluorescence start at 10 ug/mL.
• Suspention pH azide
  ADAM10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  ADAM10 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  4557251
• Ncbi nr
  NP_001101
• KDa
  85 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  102
• GENE symbol
  ADAM10
• Antigene name
  ADAM metallopeptidase domain 10
• Source
  Homo sapiens
• Protein nr
  O14672
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ADAM10  
• Gene symbol
  ADAM10
• Short name
  anti-ADAM10 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toADAM metallopeptidase domain 10 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  ADAM metallopeptidase domain 10, AD10 and AD18 and CD156c and HsT18717 and kuz and MADM and RAK, ADAM10 and IDBG-14155 and ENSG00000137845 and 102, protein homodimerization activity, nuclei, Adam10 and IDBG-182594 and ENSMUSG00000054693 and 11487, ADAM10 and IDBG-646594 and ENSBTAG00000005481 and 282132

Gene info

• Identity
  HGNC:188
• Gene
  ADAM10
• Long gene name
  ADAM metallopeptidase domain 10
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 10
• Synonyms
  • kuz
  • MADM
  • HsT18717
  • CD156C
• GenBank acession
  • AF009615
• Locus
  15q21.3
• Discovery year
  1997-03-21
• Entrez gene record
  102
• Pubmed identfication
  • 9344679
  • 9441766
• RefSeq identity
  • NM_001110
• Classification
  • ADAM metallopeptidase domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000132633

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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