Amyloid Precursor Protein Frameshift Mutant (APP, Amyloid beta (A4) Precursor Protein) Antibody
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Catalog numberMBS612160
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PricePlease ask
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Size100ul
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Alternative name1Anti-Amyloid Precursor Protein Frameshift Mutant (APP, Amyloid beta (A4) Precursor Protein)
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Alternative name2Amyloid Precursor Protein Frameshift Mutant (APP, Amyloid beta (A4) Precursor Protein)
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Alternative name3Amyloid Precursor Protein Frameshift Mutant (APP, Amyloid beta (A4) Precursor Protein)
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Alternative name4Amyloid Precursor Protein Frameshift Mutant
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Alternative name5Anti -Amyloid Precursor Protein Frameshift Mutant (APP, Amyloid beta (A4) Precursor Protein)
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Other namesamyloid protein; N/A
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesN/A
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismHost: Goat; Source: Human
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Species reactivityHuman
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Specificity and cross reactivityBinds to the truncated amyloid precursor protein frameshift mutant, which results from a GA dinucleotide deletion from the normal APP gene. This abnormal protein has been found to accumulate in the brains of some patients with Alzheimer's disease. This reagent labels dystrophic neurites in senile plaques of brains from AD patients following formalin fixation.
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Purification methodSerum.
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Form AppearanceSerum. Supplied as a liquid with 0.1% sodium azide.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze productone should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested forWestern Blot (WB), Immunohistochemistry (IHC)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional descriptionPrecursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
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French translationanticorps
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Gene target
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Gene symbolAPP-DT, APP, PABPC4, NAE1
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Short nameAmyloid Protein Frameshift Mutant (APP, Amyloid beta (A4) Protein) Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAmyloid Precursor Protein Frameshift Mutant (amyloid beta (A4) precursor protein, Amyloid b (A4) Precursor Protein) (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetamyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene nameAPP divergent transcript
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Locus
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Discovery year2020-06-12
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene nameamyloid beta precursor protein
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Synonyms gene
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Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepoly(A) binding protein cytoplasmic 4
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Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNEDD8 activating enzyme E1 subunit 1
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Synonyms gene
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Synonyms gene name
- amyloid beta precursor protein binding protein 1, 59kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ubiquitin like modifier activating enzymes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data