antibody to or anti- B-site APP-Cleaving Enzyme 1 (BACE1) Human antibody

• Catalog number
  GWB-8DD173
• Price
  Please ask
• Size
  1 vial

• Old catalog number
  18-251-405310
• Storage temperature
  store cold
• Expiry date
  1 y
• Category
  research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
• Properties
  If you buy Antibodies supplied by genways they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• French translation
  anticorps

• Gene target
  site   APP   Cleaving   Enzyme   BACE1  
• Gene symbol
  APP-DT, BACE1, BACE1-AS, APP, PABPC4, NAE1
• Short name
  antibody anti- B-site APP-Cleaving Enzyme 1 (BACE1) antibody
• Technique
  Antibody, Enzyme, anti, antibody to, antibodies against human proteins, antibodies for, enzymes
• Species
  Human, Humans
• Alternative name
  (antibody to-) to and antibody to- B-site amyloid beta (A4) precursor protein-Cleaving Enzyme 1 (BACE1) H. sapiens (antibody to-)
• Alternative technique
  antibodies, enzymes
• Alternative to gene target
  amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722

Gene info

• Identity
  HGNC:55075
• Gene
  APP-DT
• Long gene name
  APP divergent transcript
• Locus
  21q21.3
• Discovery year
  2020-06-12
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:933
• Gene
  BACE1
• Long gene name
  beta-secretase 1
• Synonyms gene
  • BACE
• Synonyms gene name
  • beta-site APP-cleaving enzyme
  • beta-site APP-cleaving enzyme 1
• GenBank acession
  • AF190725
• Locus
  11q23.3
• Discovery year
  1999-10-29
• Entrez gene record
  23621
• Pubmed identfication
  • 10531052
• Classification
  • Peptidase family A1
• VEGA ID
  OTTHUMG00000160636

Gene info

• Identity
  HGNC:37125
• Gene
  BACE1-AS
• Long gene name
  BACE1 antisense RNA
• Synonyms gene
  • BACE1AS
• Synonyms gene name
  • BACE1 antisense RNA (non-protein coding)
• Synonyms
  • FJ573250
  • NCRNA00177
  • BACE1-AS1
• Synonyms name
  • non-protein coding RNA 177
• Locus
  11q23.3
• Discovery year
  2009-07-15
• Entrez gene record
  100379571
• Pubmed identfication
  • 18587408
  • 21785702
• RefSeq identity
  • NR_037803
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000188154

Gene info

• Identity
  HGNC:620
• Gene
  APP
• Long gene name
  amyloid beta precursor protein
• Synonyms gene
  • AD1
• Synonyms gene name
  • Alzheimer disease
  • amyloid beta (A4) precursor protein
• Synonyms
  • alpha-sAPP
• Synonyms name
  • peptidase nexin-II
• GenBank acession
  • M15533
• Locus
  21q21.3
• Discovery year
  1986-01-01
• Entrez gene record
  351
• Pubmed identfication
  • 1679289
• RefSeq identity
  • NM_000484
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000078438
• Locus Specific Databases
  • Alzheimer Disease & Frontotemporal Dementia Mutation Database

Gene info

• Identity
  HGNC:8557
• Gene
  PABPC4
• Long gene name
  poly(A) binding protein cytoplasmic 4
• Synonyms gene name
  • poly(A)-binding protein, cytoplasmic 4 (inducible form)
  • poly(A) binding protein, cytoplasmic 4 (inducible form)
• Synonyms
  • iPABP
  • APP-1
• Synonyms name
  • activated-platelet protein 1
  • Inducible poly(A)-binding protein
• GenBank acession
  • U33818
• Locus
  1p34.3
• Discovery year
  1999-12-17
• Entrez gene record
  8761
• Pubmed identfication
  • 10543404
• RefSeq identity
  • NM_001135653
• Classification
  • RNA binding motif containing
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000009097

Gene info

• Identity
  HGNC:621
• Gene
  NAE1
• Long gene name
  NEDD8 activating enzyme E1 subunit 1
• Synonyms gene
  • APPBP1
• Synonyms gene name
  • amyloid beta precursor protein binding protein 1, 59kDa
• Synonyms
  • ula-1
  • APP-BP1
• GenBank acession
  • U50939
• Locus
  16q22.1
• Discovery year
  1999-01-13
• Entrez gene record
  8883
• Pubmed identfication
  • 8626687
  • 12740388
• RefSeq identity
  • NM_003905
• Classification
  • Ubiquitin like modifier activating enzymes
• VEGA ID
  OTTHUMG00000137513

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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