IL6 protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

Cytokines & Growth Factors
Reactivity

Human
Residues

Region of IL6 protein corresponding to amino acids PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM.
Type of protein

Recombinant
Expression System

Escherichia coli
Grade Purity

Grater than 98% pure
Form Buffer

Lyophilized from 10 mM Na3PO4, pH 7.5. Reconstitute with distilled water to a concentration of 0.1 - 0.5 mg/ml.
Storage

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping conditions

Blue Ice
Tested for

Please refer to the datasheet
Bioactivity

The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6 dependent Mouse 7TD1 cells is approximately 0.1 ng/ml, corresponding to a specific activity of approximately 1 x 10^7units/mg.
URL
More info
Gene

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. Recombinant, rec. E. coli interleukin-6 for cell culture or antibody production.

Gene target

IL6 protein
Gene symbol

IL6-AS1, IL6, CEBPD
Short name

IL6 protein
Alternative name

Purified recombinant Human IL6 protein
Alternative to gene target

interleukin 6 (interferon, beta 2), BSF2 and HGF and HSF and IFNB2 and IL-6, IL6 and IDBG-9462 and ENSG00000136244 and 3569, growth factor activity, Extracellular, Il6 and IDBG-144970 and ENSMUSG00000025746 and 16193, IL6 and IDBG-630280 and ENSBTAG00000014921 and 280826

Identity

HGNC:6018
Gene

IL6
Long gene name

interleukin 6
Synonyms gene
- IFNB2
Synonyms gene name
- interleukin 6 (interferon, beta 2)
Synonyms
- IL-6
- BSF2
- HGF
- HSF
Synonyms name
- interferon, beta 2
GenBank acession
- M18403
Locus

7p15.3
Discovery year

1986-01-01
Entrez gene record

3569
Pubmed identfication
- 3294161
RefSeq identity
- NM_000600
Classification
- Interleukins
- Interferons
- Interleukin 6 type cytokine family
VEGA ID

OTTHUMG00000023178

Identity

HGNC:1835
Gene

CEBPD
Long gene name

CCAAT enhancer binding protein delta
Synonyms gene name
- CCAAT/enhancer binding protein (C/EBP), delta
- CCAAT/enhancer binding protein delta
Synonyms
- CRP3
- CELF
- C/EBP-delta
- NF-IL6-beta
Locus

8q11.21
Discovery year

1992-06-24
Entrez gene record

1052
Pubmed identfication
- 1840554
- 1884998
RefSeq identity
- NM_005195
Classification
- Basic leucine zipper proteins
- CCAAT/enhancer binding proteins
VEGA ID

OTTHUMG00000162290