anti- AMPK beta 2 antibody

• Catalog number
  FNab00378
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
• Immunogen
  protein kinase, AMP-activated, beta 2 non-catalytic subunit
• Synonyms
  AMPK beta 2, AMPK subunit beta 2, PRKAB2
• Calculated MW
  35 kDa
• Uniprot ID
  O43741
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image4
  human brain tissue were subjected to SDS PAGE followed by western blot with FNab00378(PRKAB2 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AMPK   beta  
• Gene symbol
  PRKAA2
• Short name
  anti- AMPK beta 2 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- AMPK b 2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9377
• Gene
  PRKAA2
• Long gene name
  protein kinase AMP-activated catalytic subunit alpha 2
• Synonyms gene
  • PRKAA
• Synonyms gene name
  • protein kinase, AMP-activated, alpha 2 catalytic subunit
• Synonyms
  • AMPK
  • AMPKa2
• GenBank acession
  • BC069823
• Locus
  1p32.2
• Discovery year
  1995-12-12
• Entrez gene record
  5563
• Pubmed identfication
  • 7959015
• RefSeq identity
  • NM_006252
• VEGA ID
  OTTHUMG00000008282

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products