anti- ALADIN antibody

• Catalog number
  FNab00275
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
• Synonyms
  AAA, AAAS, AAASb, ADRACALA, ADRACALIN, ALADIN, DKFZp586G1624, GL003
• Calculated MW
  60 kDa
• Uniprot ID
  Q9NRG9
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human stomach cancer using FNab00275(AAAS antibody) at dilution of 1:100
• Image4
  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00275(AAAS antibody) at dilution of 1:600
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ALADIN  
• Gene symbol
  AAAS
• Short name
  anti- ALADIN antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- ALADIN (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13666
• Gene
  AAAS
• Long gene name
  aladin WD repeat nucleoporin
• Synonyms gene name
  • achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
  • achalasia, adrenocortical insufficiency, alacrimia
• Synonyms name
  • aladin
  • Allgrove, triple-A
  • adracalin
• GenBank acession
  • AJ289841
• Locus
  12q13.13
• Discovery year
  2000-11-08
• Entrez gene record
  8086
• Pubmed identfication
  • 11062474
  • 12196509
• Classification
  • WD repeat domain containing
  • Nucleoporins
• VEGA ID
  OTTHUMG00000169729

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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