CD9 monoclonal antibody
-
Catalog number1B-208-C100
-
PricePlease ask
-
Size100ug
-
-
Long nameMouse Monoclonal Antibody against Human CD9, Clone: MEM-61
-
AntigenCD9
-
Species reactivityHuman (Homo sapiens)
-
Negative species reactivityat the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
-
ClonalityMonoclonal Antibody (Mab)
-
CloneMEM-61
-
ApplicationsFC, WB, IHC(P), MC, FUNC
-
ImmunogenPre-B cell line NALM-6.
-
Format conjugationbiotin
-
SpecificityThe antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.HLDA VI; WS Code P P-15
-
Research areaCD and Related Antigens (Human)
-
Concentration1 mg/ml
-
Storage bufferPhosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
-
Shipping and storageMouse Monoclonal Antibody against Human CD9, Clone: MEM-61 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
-
BackgroundCD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
-
Purity> 95% (by SDS-PAGE)
-
Purification methodPurified by affinity chromatography
-
References*Stöckl J, Majdic O, Fischer G, Maurer D, Knapp W: Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL. J Immunol. 2001 Sep 1;167(5):2724-33., *Singh AB, Sugimoto K, Dhawan P, Harris RC: Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance. Am J Physiol Cell Physiol. 2007 Nov;293(5):C1660-8., *Lafleur MA, Xu D, Hemler ME: Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent _x000D_ pericellular proteolysis. Mol Biol Cell. 2009 Apr;20(7):2030-40., *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
-
PropertiesIf you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translationanticorps
-
Gene target
-
Gene symbolCD9
-
Short nameAnti-CD9 Mab
-
TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
HostMouse (Mus musculus)
-
IsotypeIgG1
-
Alternative nameMouse Monoclonal to CD9
-
Alternative techniqueantibodies
-
Alternative to gene targetCD9 molecule, BTCC-1 and DRAP-27 and MIC3 and MRP-1 and TSPAN-29 and TSPAN29, CD9 and IDBG-13612 and ENSG00000010278 and 928, protein binding, Extracellular, Cd9 and IDBG-189938 and ENSMUSG00000030342 and 12527, CD9 and IDBG-640522 and ENSBTAG00000014764 and 280746
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD9 molecule
-
Synonyms gene
-
Synonyms gene name
- CD9 antigen (p24)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tetraspanins
- CD molecules
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data