EpiQuik Methyl-Histone H3K4 ChIP Kit

  • Catalog number
    P-2007-48
  • Price
    Please ask
  • Size
    48 reactions
  • Storage
    Our specialists from Gentaur/Genprice advise to follow carefully the instructions for use and store the EpiQuik Methyl-Histone H3K4 ChIP Kit in refrigerator and according to the label upon arrival.
  • Tips
    Manufactured in United States. Designed for Research Use Only, not for human or animal consumption.
  • Properties
    Precipitation of Chromatins is a pull down technique of native DNA sequences by specific binding proteins on which on the other side of the protein the antibody can bind. Lots of antibodies are not suited for Chip analysis pulldown because they bind on the binding site of the DNA. The Epigen antibody is proven to not bind on the DNA binding site and is suitable for ChiP precipitation supplied in 1 vials.
  • Test
    Chromatin isolation for histone extracts like H2A, H2B, H3, and H4 extraction for SDS-PAGE electrophoresis. Histones act as spools around which DNA winds, and also play a role in gene regulation. The core histones include H2A, H2B, H3, and H4. Histones undergo post-translational modifications, which alter their interaction with DNA and nuclear proteins. The H3 and H4 histones have long tails protruding from the nucleosome, which can be covalently modified at several places (i.e., methylation, acetylation, phosphorylation, etc.). Histone modifications act in diverse biological processes such as gene regulation, DNA repair and chromosome condensation (mitosis). Combinations of modifications are thought to constitute a "histone code" and an understanding of this code may help to answer questions about human development and disease.
  • Description
    A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
  • Gene target
  • Short name
    EpiQuik Methyl-Histone H3K4 ChIP Kit
  • Technique
    Epiquik, ChiP, Chromatine immuno Precipitationg antibody, epiquik
  • Alternative name
    EpiQuik Methyl-Histone H3K4 ChIP reagent
  • Alternative technique
    epigenetic, epigenetics, kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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