Serum Amyloid A1/SAA1

• Catalog number
  E21-633
• Price
  Please ask
• Size
  10ug

• Shipping_Temperature
  Ambient
• Product_State
  Lyophilized
• Formulation_Description
  Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,1mM EDTA, pH 8.0.
• Storage
  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Reconstitution
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Background
  Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the HDL complex. The SAA cleavage product designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance.
• Alternative Names
  Serum Amyloid A-1 Protein; SAA; SAA1
• Expression system
  E.coli
• Description
  Azide Free Serum for cell culture FBS fetal bovine serum. Filtered serum for sterility. The polyclonal serum contains no red or white blood cells or clotting factors; it is the blood plasma not including the fibrinogens. Serum includes all proteins and antibodies not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances like drugs and microorganisms. Plasmas on request.
• Group
  Sera
• About
  Serum should be stored at +5°C

• Gene target
  Amyloid   A1/SAA1  
• Gene symbol
  SAA1
• Short name
  Serum Amyloid A1/SAA1
• Technique
  serum
• Species
  Human
• Alternative name
  blood serum Amyloid A1/serum amyloid A1
• Alternative technique
  sera
• Alternative to gene target
  serum amyloid A1, PIG4 and SAA and SAA2 and TP53I4, SAA1 and IDBG-34659 and ENSG00000173432 and 6288, heparin binding, Extracellular
• Tissue
  serum

Gene info

• Identity
  HGNC:10513
• Gene
  SAA1
• Long gene name
  serum amyloid A1
• Synonyms gene
  • SAA
• Synonyms
  • PIG4
  • TP53I4
• GenBank acession
  • M10906
• Locus
  11p15.1
• Discovery year
  1988-01-18
• Entrez gene record
  6288
• Pubmed identfication
  • 2595451
  • 9305847
• RefSeq identity
  • NM_199161
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000166147

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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