Recombinant Rat Thrombomodulin / THBD Protein (His tag) 20µg

• Catalog number
  PKSR030211-20µg
• Price
  Please ask
• Size
  20µg

• Synonym
  THBD
• Activity
  NA
• Sequence
  Met1-Ser517
• Fusion tag
  C-His
• Accession
  O35370
• ExpressedHost
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 90 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  55.2 kDa
• AP Mol Mass
  95 KDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Thrombomodulin, also known as THBD(CD141), is an integral membrane protein which reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome.
• Technical Data
• Conjugation
  histidine
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Thrombomodulin   THBD   Protein   His   tag   20µg  
• Gene symbol
  THBD
• Short name
  Recombinant Thrombomodulin / THBD Protein (His tag) 20µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  Rat
• Label
  His
• Species
  Rat, Rats
• Alternative name
  Rec. Rat Thrombomodulin / thrombomodulin Protein (histidine detection labelled) 20µg
• Alternative technique
  rec
• Alternative to gene target
  thrombomodulin, AHUS6 and BDCA3 and CD141 and THPH12 and THRM and TM, THBD and IDBG-59473 and ENSG00000178726 and 7056, carbohydrate binding, Extracellular, Thbd and IDBG-208962 and ENSMUSG00000074743 and 21824, THBD and IDBG-648758 and ENSBTAG00000002758 and 281529

Gene info

• Identity
  HGNC:11784
• Gene
  THBD
• Long gene name
  thrombomodulin
• Synonyms
  • CD141
  • THRM
  • BDCA-3
• Synonyms name
  • fetomodulin
• Locus
  20p11.21
• Discovery year
  2001-06-22
• Entrez gene record
  7056
• Classification
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000032053
• Locus Specific Databases
  • LRG_168

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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