Recombinant Rat Serum amyloid P component / APCS / SAP Protein (His tag)
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Catalog numberPKSR030379-50µg
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PricePlease ask
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Size50µg
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SynonymSap
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ActivityNA
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SequenceMet 1-Ser 228
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Fusion tagC-His
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AccessionP23680
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ExpressedHostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity> 95 % as determined by SDS-PAGE
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Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass25.3 kDa
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AP Mol Mass30 KDa
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FormulationLyophilized from sterile PBS, pH 7.4
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BackgroundSerum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.
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Conjugationhistidine
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats. Serum should be stored at +5°C
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Latin nameRattus norvegicus
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SourceRecombinants or rec. proteins
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Grouprecombinants, Sera
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DescriptionAzide Free Serum for cell culture FBS fetal bovine serum. Filtered serum for sterility. The polyclonal serum contains no red or white blood cells or clotting factors; it is the blood plasma not including the fibrinogens. Serum includes all proteins and antibodies not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances like drugs and microorganisms. Plasmas on request.
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Gene target
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Gene symbolAPCS, GM2A, PTPRH, DLG1, DLG4, SH2D1A, DLG3
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Short nameRecombinant Serum amyloid P component / APCS / SAP Protein (His tag)
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TechniqueRecombinant, serum, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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HostRat
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LabelHis
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SpeciesRat, Rats
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Alternative nameRec. Rat blood serum amyloid P component / amyloid P component, serum / SAP Protein (histidine detection labelled)
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Alternative techniquerec, sera
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Alternative to gene targetamyloid P component, serum, HEL-S-92n and PTX2 and SAP, APCS and IDBG-103905 and ENSG00000132703 and 325, unfolded protein binding, nuclei, Apcs and IDBG-205704 and ENSMUSG00000026542 and 20219, APCS and IDBG-630753 and ENSBTAG00000019616 and 514488
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Tissueserum
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Gene info
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Identity
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Gene
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Long gene nameamyloid P component, serum
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Short pentraxins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameGM2 ganglioside activator
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Synonyms gene name
- GM2 ganglioside activator protein
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type H
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Synonyms
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Locus
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Discovery year1994-09-14
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namediscs large MAGUK scaffold protein 1
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Synonyms gene name
- discs, large homolog 1 (Drosophila)
- discs large homolog 1, scribble cell polarity complex component
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-05-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- MicroRNA protein coding host genes
- Scribble complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namediscs large MAGUK scaffold protein 4
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Synonyms gene name
- discs, large homolog 4 (Drosophila)
- discs large homolog 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-11-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Membrane associated guanylate kinases
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSH2 domain containing 1A
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Synonyms gene
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Synonyms gene name
- lymphoproliferative syndrome
- SH2 domain protein 1A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namediscs large MAGUK scaffold protein 3
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Synonyms gene name
- discs, large homolog 3 (neuroendocrine-dlg, Drosophila)
- discs, large homolog 3 (Drosophila)
- discs large homolog 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
