Recombinant Mouse Biglycan / PG-S1 / BGN Protein (Fc tag)
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Catalog numberPKSM040496-50µg
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PricePlease ask
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Size50µg
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SynonymBG;DSPG1;PG-S1;PGI;SLRR1A
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ActivityNA
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SequenceMet1-Lys369
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Fusion tagC-Fc
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AccessionNA
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Expressed HostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity> 85 % as determined by SDS-PAGE
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Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass66.5 kDa
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AP Mol Mass67 kDa
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FormulationLyophilized from sterile PBS, pH 7.4
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BackgroundBiglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolPGS1, BGN, TPGS1, PSMD1, EPYC, VCAN, IL22RA2, JUP, EFEMP1, PPIB
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Short nameRecombinant Mouse Biglycan / PG-S1 / BGN Protein (Fc tag)
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TechniqueRecombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Hostmouse
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LabelFc Tag
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SpeciesMouse, Mouses
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Alternative nameRec. Mouse Biglycan / PG-S1 / BGN Protein (fragment c detection labelled)
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Alternative techniquerec, murine
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Gene info
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Identity
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Gene
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Long gene namephosphatidylglycerophosphate synthase 1
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Synonyms
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Locus
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Discovery year2005-11-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebiglycan
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-07-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small leucine rich repeat proteoglycans
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametubulin polyglutamylase complex subunit 1
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Synonyms gene
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Synonyms gene name
- chromosome 19 open reading frame 20
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproteasome 26S subunit, non-ATPase 1
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Synonyms gene name
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-11-28
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Entrez gene record
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Pubmed identfication
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Classification
- Proteasome
- Armadillo like helical domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameepiphycan
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Synonyms gene
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Synonyms gene name
- dermatan sulphate proteoglycan 3
- dermatan sulfate proteoglycan 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-05-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small leucine rich repeat proteoglycans
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameversican
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Synonyms gene
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Synonyms gene name
- chondroitin sulfate proteoglycan 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-07-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-type lectin domain containing
- Sushi domain containing
- Hyalectan proteoglycans
- V-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 22 receptor subunit alpha 2
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Synonyms gene name
- interleukin 22 receptor, alpha 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-02
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Entrez gene record
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Pubmed identfication
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Classification
- Interleukin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namejunction plakoglobin
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Synonyms gene
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Synonyms gene name
- catenin (cadherin-associated protein), gamma 80kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-03-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Beta catenins
- Armadillo repeat containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameEGF containing fibulin extracellular matrix protein 1
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Synonyms gene
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Synonyms gene name
- fibrillin-like
- EGF-containing fibulin-like extracellular matrix protein 1
- EGF containing fibulin like extracellular matrix protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-04-30
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Entrez gene record
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Pubmed identfication
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Classification
- Fibulins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepeptidylprolyl isomerase B
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-11-25
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Entrez gene record
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Pubmed identfication
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Classification
- Cyclophilin peptidylprolyl isomerases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data