Recombinant Mouse Biglycan / PG-S1 / BGN Protein (Fc tag)

• Catalog number
  PKSM040496-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  BG;DSPG1;PG-S1;PGI;SLRR1A
• Activity
  NA
• Sequence
  Met1-Lys369
• Fusion tag
  C-Fc
• Accession
  NA
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 85 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  66.5 kDa
• AP Mol Mass
  67 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
• Technical data
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Biglycan   PG-S1   BGN   Protein   tag  
• Gene symbol
  PGS1, BGN, TPGS1, PSMD1, EPYC, VCAN, IL22RA2, JUP, EFEMP1, PPIB
• Short name
  Recombinant Mouse Biglycan / PG-S1 / BGN Protein (Fc tag)
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  Fc Tag
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Biglycan / PG-S1 / BGN Protein (fragment c detection labelled)
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:30029
• Gene
  PGS1
• Long gene name
  phosphatidylglycerophosphate synthase 1
• Synonyms
  • DKFZP762M186
• Locus
  17q25.3
• Discovery year
  2005-11-15
• Entrez gene record
  9489
• Pubmed identfication
  • 9880566
• RefSeq identity
  • NM_024419
• VEGA ID
  OTTHUMG00000177514

Gene info

• Identity
  HGNC:1044
• Gene
  BGN
• Long gene name
  biglycan
• Synonyms
  • DSPG1
  • SLRR1A
• Synonyms name
  • biglycan proteoglycan
• GenBank acession
  • AK092954
• Locus
  Xq28
• Discovery year
  1989-07-18
• Entrez gene record
  633
• Pubmed identfication
  • 1612609
• RefSeq identity
  • NM_001711
• Classification
  • Small leucine rich repeat proteoglycans
• VEGA ID
  OTTHUMG00000024205
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:25058
• Gene
  TPGS1
• Long gene name
  tubulin polyglutamylase complex subunit 1
• Synonyms gene
  • C19orf20
• Synonyms gene name
  • chromosome 19 open reading frame 20
• Synonyms
  • GTRGEO22
  • PGs1
• GenBank acession
  • BC009520
• Locus
  19p13.3
• Discovery year
  2004-03-16
• Entrez gene record
  91978
• Pubmed identfication
  • 11441184
  • 12972506
• RefSeq identity
  • NM_033513
• VEGA ID
  OTTHUMG00000180557

Gene info

• Identity
  HGNC:9554
• Gene
  PSMD1
• Long gene name
  proteasome 26S subunit, non-ATPase 1
• Synonyms gene name
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
• Synonyms
  • S1
  • P112
  • Rpn2
• GenBank acession
  • D44466
• Locus
  2q37.1
• Discovery year
  1995-11-28
• Entrez gene record
  5707
• Pubmed identfication
  • 8816993
• Classification
  • Proteasome
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000133223

Gene info

• Identity
  HGNC:3053
• Gene
  EPYC
• Long gene name
  epiphycan
• Synonyms gene
  • DSPG3
• Synonyms gene name
  • dermatan sulphate proteoglycan 3
  • dermatan sulfate proteoglycan 3
• Synonyms
  • Pg-Lb
  • SLRR3B
• Synonyms name
  • epiphycan proteoglycan
• GenBank acession
  • AF031658
• Locus
  12q21.33
• Discovery year
  1996-05-30
• Entrez gene record
  1833
• Pubmed identfication
  • 8975717
• RefSeq identity
  • NM_004950
• Classification
  • Small leucine rich repeat proteoglycans
• VEGA ID
  OTTHUMG00000170072

Gene info

• Identity
  HGNC:2464
• Gene
  VCAN
• Long gene name
  versican
• Synonyms gene
  • CSPG2
• Synonyms gene name
  • chondroitin sulfate proteoglycan 2
• Synonyms
  • PG-M
• Synonyms name
  • versican proteoglycan
• GenBank acession
  • X15998
• Locus
  5q14.2-q14.3
• Discovery year
  1991-07-18
• Entrez gene record
  1462
• Pubmed identfication
  • 1478664
  • 21063030
• RefSeq identity
  • NM_004385
• Classification
  • C-type lectin domain containing
  • Sushi domain containing
  • Hyalectan proteoglycans
  • V-set domain containing
• VEGA ID
  OTTHUMG00000131321

Gene info

• Identity
  HGNC:14901
• Gene
  IL22RA2
• Long gene name
  interleukin 22 receptor subunit alpha 2
• Synonyms gene name
  • interleukin 22 receptor, alpha 2
• Synonyms
  • CRF2-S1
  • IL-22BP
• GenBank acession
  • AY044429
• Locus
  6q23.3
• Discovery year
  2002-12-02
• Entrez gene record
  116379
• Pubmed identfication
  • 11481447
  • 11390454
• Classification
  • Interleukin receptors
• VEGA ID
  OTTHUMG00000015655

Gene info

• Identity
  HGNC:6207
• Gene
  JUP
• Long gene name
  junction plakoglobin
• Synonyms gene
  • CTNNG
• Synonyms gene name
  • catenin (cadherin-associated protein), gamma 80kDa
• Synonyms
  • DP3
  • PDGB
  • PKGB
  • DPIII
  • PG
• Synonyms name
  • desmosomal protein 3
• GenBank acession
  • AF233882
• Locus
  17q21.2
• Discovery year
  1991-03-04
• Entrez gene record
  3728
• Pubmed identfication
  • 1889810
  • 7604000
• RefSeq identity
  • NM_001352773
• Classification
  • Beta catenins
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000133494
• Locus Specific Databases
  • Gene Connection for the Heart; Naxos disease database
  • Global Variome shared LOVD
  • LRG_401

Gene info

• Identity
  HGNC:3218
• Gene
  EFEMP1
• Long gene name
  EGF containing fibulin extracellular matrix protein 1
• Synonyms gene
  • DHRD
  • FBNL
• Synonyms gene name
  • fibrillin-like
  • EGF-containing fibulin-like extracellular matrix protein 1
  • EGF containing fibulin like extracellular matrix protein 1
• Synonyms
  • S1-5
  • FBLN3
  • MTLV
• Synonyms name
  • fibulin 3
• GenBank acession
  • U03877
• Locus
  2p16.1
• Discovery year
  1996-04-30
• Entrez gene record
  2202
• Pubmed identfication
  • 8812496
  • 7799918
• Classification
  • Fibulins
• VEGA ID
  OTTHUMG00000129343
• Locus Specific Databases
  • Mutations of the EGF-containing fibulin-like extracellular matrix protein 1

Gene info

• Identity
  HGNC:9255
• Gene
  PPIB
• Long gene name
  peptidylprolyl isomerase B
• Synonyms
  • CYPB
  • OI9
  • PPIase
  • B
  • CYP-S1
  • SCYLP
• Synonyms name
  • cyclophilin B
  • peptidyl-prolyl cis-trans isomerase B
  • rotamase B
  • S-cyclophilin
• Locus
  15q22.31
• Discovery year
  1991-11-25
• Entrez gene record
  5479
• Pubmed identfication
  • 2000394
  • 20089953
• Classification
  • Cyclophilin peptidylprolyl isomerases
• VEGA ID
  OTTHUMG00000133018
• Locus Specific Databases
  • Osteogenesis Imperfecta Variant Database
  • LRG_10

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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