Recombinant Human DPP7 / DPPII / DPP2 Protein (His tag)

• Catalog number
  PKSH031447-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  DPP2;DPPII;QPP
• Activity
  NA
• Sequence
  Met 1-Leu 492
• Fusion tag
  C-His
• Accession
  NP_037511.2
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞98 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  53.6 kDa
• AP Mol Mass
  60 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis.
• Technical data
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  DPP7   DPPII   DPP2   Protein   His   tag  
• Gene symbol
  DPP7
• Short name
  Recombinant DPP7 / DPPII / DPP2 Protein (His tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens DPP7 / DPPII / DPP2 Protein (histidine detection labelled)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:14892
• Gene
  DPP7
• Long gene name
  dipeptidyl peptidase 7
• Synonyms gene name
  • dipeptidylpeptidase 7
• Synonyms
  • DPPII
  • DPP2
• GenBank acession
  • AF154502
• Locus
  9q34.3
• Discovery year
  2001-04-20
• Entrez gene record
  29952
• Pubmed identfication
  • 10477574
  • 11139392
• RefSeq identity
  • NM_013379
• Classification
  • DASH family
• VEGA ID
  OTTHUMG00000020977

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products