Recombinant Human BCL6 / B-cell CLL lymphoma 6 Protein (aa 1-150, His & Trx tag)

• Catalog number
  PKSH030910-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  BCL5;BCL6A;LAZ3;ZBTB27;ZNF51
• Activity
  NA
• Sequence
  Met 1-Met 150
• Fusion tag
  N-His & Trx
• Accession
  P41182
• Expressed Host
  E. coli
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞92 % as determined by SDS-PAGE
• Endotoxin
  Please contact us for more information.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  34.2 kDa
• AP Mol Mass
  33 kDa
• Formulation
  Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.0
• Background
  The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.
• Technical data
• Description
  For cells, cell lines and tissues in culture till half confluency.
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  BCL6   CLL   lymphoma   Protein   1-150   His   Trx   tag  
• Gene symbol
  BCL6-AS1, CLEC12A, ZNF212, MIR150, GLOD4, BCL6, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1
• Short name
  Recombinant BCL6 / B- CLL lymphoma 6 Protein (aa 1-150, His & Trx tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens B-cellular CLL/lymphoma 6 / B-cellular CLL lymphoma 6 Protein (aa 1-150, histidine & Trx detection labelled)
• Alternative technique
  rec
• Alternative to gene target
  B-cell CLL/lymphoma 6, BCL5 and BCL6A and LAZ3 and ZBTB27 and ZNF51, BCL6 and IDBG-69349 and ENSG00000113916 and 604, metal ion binding, nuclei, Bcl6 and IDBG-149890 and ENSMUSG00000022508 and 12053, BCL6 and IDBG-634562 and ENSBTAG00000001511 and 539020
• Tissue
  cell

Gene info

• Identity
  HGNC:51843
• Gene
  BCL6-AS1
• Long gene name
  BCL6 antisense RNA 1
• Synonyms gene name
  • BCL6 antisense 1
• Synonyms
  • lnc-RP11-211G3.3.1-1
• Locus
  3q27.3
• Discovery year
  2017-08-03
• Entrez gene record
  106146153
• Pubmed identfication
  • 26276666
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:31713
• Gene
  CLEC12A
• Long gene name
  C-type lectin domain family 12 member A
• Synonyms gene name
  • C-type lectin domain family 12, member A
• Synonyms
  • CLL-1
  • MICL
  • CD371
  • DCAL-2
• Synonyms name
  • dendritic cell-associated lectin 2
  • myeloid inhibitory C-type lectin-like receptor
• GenBank acession
  • AY498550
• Locus
  12p13.31
• Discovery year
  2005-02-09
• Entrez gene record
  160364
• RefSeq identity
  • NM_138337
• Classification
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168396

Gene info

• Identity
  HGNC:13004
• Gene
  ZNF212
• Long gene name
  zinc finger protein 212
• Synonyms
  • C2H2-150
• GenBank acession
  • U38864
• Locus
  7q36.1
• Discovery year
  1999-09-29
• Entrez gene record
  7988
• Pubmed identfication
  • 9169157
• RefSeq identity
  • NM_012256
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000158968

Gene info

• Identity
  HGNC:31537
• Gene
  MIR150
• Long gene name
  microRNA 150
• Synonyms gene
  • MIRN150
• Synonyms
  • hsa-mir-150
• Locus
  19q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406942
• Pubmed identfication
  • 23159943
• RefSeq identity
  • NR_029703
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:14111
• Gene
  GLOD4
• Long gene name
  glyoxalase domain containing 4
• Synonyms gene
  • C17orf25
• Synonyms gene name
  • chromosome 17 open reading frame 25
• Synonyms
  • CGI-150
  • HC71
• GenBank acession
  • AF177342
• Locus
  17p13.3
• Discovery year
  2004-06-24
• Entrez gene record
  51031
• Pubmed identfication
  • 11642406
  • 12528892
• RefSeq identity
  • NM_016080
• Classification
  • Glyoxalase domain containing family
• VEGA ID
  OTTHUMG00000177497

Gene info

• Identity
  HGNC:1001
• Gene
  BCL6
• Long gene name
  BCL6 transcription repressor
• Synonyms gene
  • ZNF51
• Synonyms gene name
  • zinc finger protein 51
  • B cell CLL/lymphoma 6
  • BCL6, transcription repressor
• Synonyms
  • ZBTB27
  • LAZ3
  • BCL5
  • BCL6A
• Locus
  3q27.3
• Discovery year
  1993-04-12
• Entrez gene record
  604
• Pubmed identfication
  • 8057668
• RefSeq identity
  • NM_001706
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000156441

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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