Rabbit Anti Human USP15 Antibody-Non-conjugated

  • Catalog number
    CSB-PA896515DSR2HU_50ul
  • Price
    Please ask
  • Size
    50ul
  • Long name
    Rabbit Antibody against Human USP15, Non-conjugated
  • Synonym name
    USP15 Human Antibody
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,IHC;Recommended dilution:IHC:1:20-1:200
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    Q9Y4E8
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Purity
    >95%
  • Purification method
    Antigen Affinity Purified Antibodies
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Ubiquitin carboxyl-terminal hydrolase 15 protein (1-260AA)
  • Immunogen species
    Human
  • Alias
    Ubiquitin carboxyl-terminal hydrolase 15,Deubiquitinating enzyme 15,Ubiquitin thioesterase 15,Ubiquitin-specific-processing protease 15,Unph-2,Unph4,USP15,KIAA0529
  • Background
    Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling and NF-kappa-B pathways. Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear: according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes (PubMed:21947082). According to another reports, regulates the TGF-beta receptor signaling pathway by mediating deubiquitination and stabilization of TGFBR1, leading to an enhanced TGF-beta signal (PubMed:22344298). Able to mediate deubiquitination of monoubiquitinated substrates as well as 'Lys-48'-linked polyubiquitin chains, protecting them against proteasomal degradation. May also regulate gene expression and/or DNA repair through the deubiquitination of histone H2B (PubMed:24526689). Acts as an associated component of COP9 signalosome complex (CSN) and regulates different pathways via this association: regulates NF-kappa-B by mediating deubiquitination of NFKBIA and deubiquitinates substrates bound to VCP. Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    USP15 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Ubiquitin carboxyl-terminal hydrolase 15
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
  • Properties
    If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    USP15
  • Short name
    Anti-USP15
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Host
    Rabbit, Rabbits
  • Species
    Human, Humans
  • Alternative name
    USP15 Antibody
  • Alternative technique
    antibodies, rabbit-anti
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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