Rabbit Anti Human SGMS1 Antibody-Non-conjugated
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Catalog numberCSB-PA801243LA01HU_50ug
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Price:
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Size50ug
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Long nameRabbit Antibody against Human SGMS1, Non-conjugated
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Synonym nameSGMS1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ86VZ5
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 1 protein (48-137AA)
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Immunogen speciesHuman
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AliasPhosphatidylcholine:ceramide cholinephosphotransferase 1 ,Medulla oblongata-derived protein,Protein Mob,Sphingomyelin synthase 1,Transmembrane protein 23,SGMS1,MOB,SMS1,TMEM23
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BackgroundSphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
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ClonalityPolyclonal antibody
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Shipping and storageSGMS1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenPhosphatidylcholine:ceramide cholinephosphotransferase 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolSGMS1-AS1, SGMS1
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Short nameAnti-SGMS1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameSGMS1 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetsphin this GO myelin synthase 1, SGMS1 and IDBG-74409 and ENSG00000198964 and 259230, ceramide cholinephosphotransferase activity, nuclei, Sgms1 and IDBG-158524 and ENSMUSG00000040451 and 208449, SGMS1 and IDBG-637178 and ENSBTAG00000011748 and 533538
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Gene info
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Identity
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Gene
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Long gene nameSGMS1 antisense RNA 1
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Locus
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Discovery year2014-02-01
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Entrez gene record
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesphingomyelin synthase 1
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Synonyms gene
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Synonyms gene name
- transmembrane protein 23
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-03-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sterile alpha motif domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data