Rabbit Anti Human CNTN1 Antibody-Biotin

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• Catalog number
  CSB-PA623657LD01HU_100ug
• Price:

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• Size
  100ug

# #

• Long name
  Rabbit Antibody against Human CNTN1, Biotin
• Synonym name
  CNTN1 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA
• Conjugation
  Biotin
• Antibody isotype
  IgG
• UniProt ID
  Q12860
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Contactin-1 protein (686-866AA)
• Immunogen species
  Human
• Alias
  Contactin-1, Glycoprotein gp135, Neural cell surface protein F3, CNTN1
• Background
  Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).
• Clonality
  Polyclonal antibody
• Shipping and storage
  CNTN1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Contactin-1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional conjugation
  Biotinylated
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

#

• Gene target
  CNTN1  
• Gene symbol
  CNTN1
• Short name
  Anti-CNTN1
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
• Host
  Rabbit, Rabbits
• Label
  Biotin
• Species
  Human, Humans
• Alternative name
  CNTN1 Antibody,Biotin conjugated
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  contactin 1, F3 and GP135 and MYPCN, CNTN1 and IDBG-27462 and ENSG00000018236 and 1272, carbohydrate binding, Plasma membranes, Cntn1 and IDBG-176351 and ENSMUSG00000055022 and 12805, CNTN1 and IDBG-633416 and ENSBTAG00000020679 and 281705

Gene info

• Identity
  HGNC:2171
• Gene
  CNTN1
• Long gene name
  contactin 1
• Synonyms
  • F3
  • GP135
• Synonyms name
  • glycoprotein gP135
• GenBank acession
  • Z21488
• Locus
  12q12
• Discovery year
  1994-02-18
• Entrez gene record
  1272
• Pubmed identfication
  • 7959734
  • 8586965
• RefSeq identity
  • NM_001843
• Classification
  • I-set domain containing
  • Contactins
• VEGA ID
  OTTHUMG00000169362

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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