Human E3 ubiquitin-protein ligase TRIM21 (TRIM21)

• Catalog number
  CSB-EP024457HU-500ug
• Price
  Please ask
• Size
  500ug

• Description
  Recombinant Human E3 ubiquitin-protein ligase TRIM21(TRIM21) expressed in E.coli
• Specifications
  Uniprot ID: P19474; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-475aa; Sequence information: Full Length; Tag: N-terminal 6xHis-tagged; Purity: Greater than 85% as determined by SDS-PAGE.
• Additional_information
  MW: 58.2 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  ubiquitin-protein   ligase   TRIM21   TRIM21  
• Gene symbol
  TRIM21
• Short name
  E3 ubiquitin-protein ligase TRIM21 (TRIM21)
• Species
  Human, Humans
• Alternative name
  H. sapiens E3 ubiquitin-protein ligase TRIM21 (TRIM21)

Gene info

• Identity
  HGNC:11312
• Gene
  TRIM21
• Long gene name
  tripartite motif containing 21
• Synonyms gene
  • SSA1
• Synonyms gene name
  • Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro)
  • tripartite motif-containing 21
• Synonyms
  • RNF81
  • RO52
• Synonyms name
  • Ro/SSA 52kDa
  • E3 ubiquitin-protein ligase TRIM21
• GenBank acession
  • AF391283
• Locus
  11p15.4
• Discovery year
  1994-01-06
• Entrez gene record
  6737
• Pubmed identfication
  • 8094596
• RefSeq identity
  • NM_003141
• Classification
  • Tripartite motif containing
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000165701

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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