Suppressors Of Cytokine Signaling 2 (SOCS2) Polyclonal Antibody (Rat), HRP

• Catalog number
  PAH154Ra01-100ul-HRP
• Price
  Please ask
• Size
  100ul

• Description
  A Rabbit polyclonal antibody against Rat Suppressors Of Cytokine Signaling 2 (SOCS2). This antibody is labeled with HRP.
• Specifications
  Host: Rabbit; Species Reactivity: Rat; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: HRP
• Additional_information
  Sequence of the immunogen: SOCS2 (Met1~Val198); Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional description
  Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
• Conjugation
  HRP Conjugated
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• French translation
  anticorps

• Gene target
  Suppressors   Cytokine   Signaling   SOCS2  
• Gene symbol
  SOCS2-AS1, SOCS2
• Short name
  Suppressors Of Cytokine Signaling 2 (SOCS2) Polyclonal Antibody ( ),
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rat
• Label
  HRP
• Species
  Rat, Rats
• Alternative name
  Suppressors on Cytokine Signaling 2 (suppressor on cytokine signaling 2) polyclonal (antibody to-) (Rat), horseradish peroxidase
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  suppressor of cytokine signaling 2, CIS2 and Cish2 and SOCS-2 and SSI-2 and SSI2 and STATI2, SOCS2 and IDBG-51299 and ENSG00000120833 and 8835, JAK pathway signal transduction adaptor activity, Cytoplasm, SOCS2 and IDBG-630845 and ENSBTAG00000012007 and 338437

Gene info

• Identity
  HGNC:27054
• Gene
  SOCS2-AS1
• Long gene name
  SOCS2 antisense RNA 1
• Synonyms gene name
  • SOCS2 antisense RNA 1 (non-protein coding)
• Locus
  12q22
• Discovery year
  2012-06-30
• Entrez gene record
  144481
• Pubmed identfication
  • 24168098
• RefSeq identity
  • NR_038263
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000170159

Gene info

• Identity
  HGNC:19382
• Gene
  SOCS2
• Long gene name
  suppressor of cytokine signaling 2
• Synonyms
  • STATI2
  • SSI2
  • SOCS-2
  • SSI-2
  • CIS2
  • Cish2
• Synonyms name
  • STAT-induced STAT inhibitor-2
• GenBank acession
  • AF037989
• Locus
  12q
• Discovery year
  2002-11-13
• Entrez gene record
  8835
• Pubmed identfication
  • 9344848
  • 9266833
• Classification
  • Suppressors of cytokine signaling
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000170160

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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