OVA Conjugated Homing Associated Cell Adhesion Molecule (HCAM)
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Catalog number
CPA670Hu21-50ug
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Price
Please ask
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Size
50ug
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Description
Recombinant Human Homing Associated Cell Adhesion Molecule expressed in: Protein conjugation
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Specifications
Host species: Homo sapiens (Human); Expression system: Protein conjugation; Expression region: Tyr155InquireIle168; Purity: > 90%; Endotoxin level:
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Additional_information
Uniprot ID: P16070; Buffer composition: PBS, pH 7.4.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): Inquire; Isoelectric Point: Inquire
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Storage_and_shipping
Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
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Notes
Research Use Only.
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Additional description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the OVA Conjugated Homing Associated Adhesion Molecule (HCAM). For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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