Mouse Anti OVA Monoclonal IgE Antibody E-C1, 1 mg, lyophilized

• Catalog number
  3006
• Price
  Please ask
• Size
  1 vial

• Tech file
• Data sheet
• References
  ELISA kits for collagen and chondrocytes more
• Other chondrocytes and synoviocytes
• References of collagen and chondrocyte research and assays
  Kim W.­U., Yoo W.­H., Won Park, Kang Y.­M., Kim S.­I., Park J.­H., Lee S.­S., Joo Y.­S, Min J.­  K., Hong Y.­S., Lee S.­H., Park S.­H., Cho C.­S., Kim H.­Y. IgG antibodies to type II collagen reflect inflammatory activity in patients with rheumatoid arthritis. Journal of Rheumatology, 2000; 27(3):575­581. Terato K., DeArmey D.A., Ye X.J., Griffiths M.M., Cremer M.A. The Mechanism of Autoantibody  Formation to Cartilage in Rheumatoid Arthritis: Possible Cross­Reaction of Antibodies to Dietary  Collagens with Autologous Type II Collagen. Clin Imm Immunopath, 1996; 79(2):142­154(13)  Terato K, Shimozuru Y, Katayama K, et al. Specificity of antibodies to type II collagen in rheumatoid arthritis. Arthritis Rheum 1990;33:1493­500. Clague RB, Moore LJ. IgG and IgM antibody to native type II collagen in rheumatoid serum and synovial fluid: evidence for the presence of collagen­anticollagen immune complexes in synovial fluid. Arthritis Rheum 1984;27:1370­7. Fujii K, Tsuji M, Kitamura A, Murota K. The diagnostic significance of anti­type II collagen antibody assay in rheumatoid arthritis. Int Orthop 1992;16:272­6.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by Chondrocytes and collagens they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• About
  The term “freeze-dry” is a lay description for the process of lyophilization protein powder. It is the conversion of water from a frozen state to a gaseous state without going through a liquid state. Aliquoting with 25 mM HEPES-KOH, pH 7.2 and 1 mM DTT and 10% weight on volume glycerol is suitable for storage of the reconstituted powder. The freeze-dry process removes moisture from the cells of specimens while the specimens remain frozen. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Gene
  Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
• French translation
  anticorps

• Gene target
  OVA   Monoclonal   E-C1  
• Gene symbol
  SNAR-C1, HLA-E, TRGC1, SMC2, SNAR-E, PFDN4, IPCEF1, SNRPE, KLRC3
• Short name
  Mouse Anti OVA Monoclonal IgE Antibody E-C1, 1 mg,
• Technique
  Antibody, Mouse, anti, IgE, antibody to, antibodies against human proteins, antibodies for, IgEs, Monoclonals or monoclonal antibodies, mouses
• Host
  mouse
• Isotype
  IgE, IgE
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to OVA monoclonal immunoglobuline E (antibody to-) E-C1, 1 mg, lyophilized
• Alternative technique
  antibodies, murine, immunoglobulin-e

Gene info

• Identity
  HGNC:34319
• Gene
  SNAR-C1
• Long gene name
  small NF90 (ILF3) associated RNA C1
• Synonyms gene name
  • small ILF3/NF90-associated RNA C1
• GenBank acession
  • EU071066
• Locus
  19q13.32
• Discovery year
  2008-07-03
• Entrez gene record
  100170225
• Pubmed identfication
  • 17855395
• RefSeq identity
  • NR_024220
• Classification
  • Small NF90 (ILF3) associated RNAs

Gene info

• Identity
  HGNC:4962
• Gene
  HLA-E
• Long gene name
  major histocompatibility complex, class I, E
• GenBank acession
  • M20022
• Locus
  6p22.1
• Discovery year
  1988-05-11
• Entrez gene record
  3133
• Pubmed identfication
  • 3131426
• RefSeq identity
  • NM_005516
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031155
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:12275
• Gene
  TRGC1
• Long gene name
  T cell receptor gamma constant 1
• Synonyms gene
  • TCRGC1
• Synonyms gene name
  • TCRGC1
• Synonyms
  • C1
• Synonyms name
  • T-cell receptor, gamma, constant region C1
• GenBank acession
  • M14996
• Locus
  7p14.1
• Discovery year
  1989-05-30
• Entrez gene record
  6966
• Pubmed identfication
  • 2879283
• RefSeq identity
  • NG_001336
• Classification
  • T cell receptor gamma locus at 7p14
• VEGA ID
  OTTHUMG00000155219

Gene info

• Identity
  HGNC:14011
• Gene
  SMC2
• Long gene name
  structural maintenance of chromosomes 2
• Synonyms gene
  • SMC2L1
• Synonyms gene name
  • SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
  • SMC2 structural maintenance of chromosomes 2-like 1 (yeast)
• Synonyms
  • hCAP-E
  • CAP-E
• GenBank acession
  • AF092563
• Locus
  9q31.1
• Discovery year
  2001-02-22
• Entrez gene record
  10592
• Pubmed identfication
  • 9789013
• Classification
  • Condensin I subunits
  • Condensin II subunits
  • Structural maintenance of chromosomes proteins
• VEGA ID
  OTTHUMG00000020401

Gene info

• Identity
  HGNC:34325
• Gene
  SNAR-E
• Long gene name
  small NF90 (ILF3) associated RNA E
• Synonyms gene name
  • small ILF3/NF90-associated RNA E
• GenBank acession
  • EU071072
• Locus
  19q13.32
• Discovery year
  2008-07-03
• Entrez gene record
  100170220
• Pubmed identfication
  • 17855395
• RefSeq identity
  • NR_024258
• Classification
  • Small NF90 (ILF3) associated RNAs

Gene info

• Identity
  HGNC:8868
• Gene
  PFDN4
• Long gene name
  prefoldin subunit 4
• Synonyms gene name
  • prefoldin 4
• Synonyms
  • PFD4
  • C-1
  • C1
• GenBank acession
  • U41816
• Locus
  20q13.2
• Discovery year
  1998-08-06
• Entrez gene record
  5203
• Pubmed identfication
  • 9630229
  • 8744932
• RefSeq identity
  • NM_002623
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000032775

Gene info

• Identity
  HGNC:21204
• Gene
  IPCEF1
• Long gene name
  interaction protein for cytohesin exchange factors 1
• Synonyms
  • PIP3-E
  • KIAA0403
• Synonyms name
  • phosphoinositide binding protein PIP3-E
• GenBank acession
  • AB007863
• Locus
  6q25.2
• Discovery year
  2009-02-27
• Entrez gene record
  26034
• Pubmed identfication
  • 11804589
  • 19756519
• RefSeq identity
  • NM_001130699
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000015872

Gene info

• Identity
  HGNC:11161
• Gene
  SNRPE
• Long gene name
  small nuclear ribonucleoprotein polypeptide E
• Synonyms
  • Sm-E
• GenBank acession
  • M37716
• Locus
  1q32.1
• Discovery year
  1988-11-28
• Entrez gene record
  6635
• Pubmed identfication
  • 1835977
  • 2143747
• RefSeq identity
  • NM_003094
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000035985

Gene info

• Identity
  HGNC:6376
• Gene
  KLRC3
• Long gene name
  killer cell lectin like receptor C3
• Synonyms gene name
  • killer cell lectin-like receptor subfamily C, member 3
• Synonyms
  • NKG2-E
• GenBank acession
  • L14542
• Locus
  12p13.2
• Discovery year
  1998-01-16
• Entrez gene record
  3823
• Pubmed identfication
  • 9598306
• RefSeq identity
  • NM_002261
• Classification
  • C-type lectin domain containing
  • Killer cell lectin like receptors
• VEGA ID
  OTTHUMG00000167149

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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