OxiSelect DNA Double Strand Break (DSB) Staining Kit, Trial Size
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Catalog number
STA-321-T
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Price
Please ask
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Size
20 assays
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Shipping Temp
Blue Ice
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Storage Temp
-20ºC
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Category Product Type
Kit
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URL link to SDS
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UNSPSC
41116100
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Product Line
Oxidative Stress/Damage
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Short Description
Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect™ DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX.
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Product feature 1
Detects phosphorylation of histone H2A.X
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Product feature 2
See immunofluorescence in about 3 hours
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Product feature 3
DNA double-strand break inducer included
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Gene target
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Gene symbol
PRKDC, HLA-DOA
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Short name
OxiSelect DNA Double Strand Break (DSB) Staining Kit, Trial Size
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Technique
dna
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Alternative name
OxiSelect Desoxyribonucleic acid Double Strand Break (DSB) coloring reagent, Trial Size
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Alternative technique
kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
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Tree numbers
- E01.370.225.812.735.830
- E05.200.812.735.830
- E05.478.566.380.810
- E05.478.566.639.810
- E05.478.594.760.830
- E05.601.470.380.810
- E05.601.470.639.810
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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