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Target antigen
SLC2A5
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, rat Predicted to work with: mouse
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Analyses
WB,IHC-P,IHC-F
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Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse SLC2A5(232-251aa ALQTLRGWKDVHLEMEEIRK), different from the related rat sequence by two amino acids.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the SLC2A5 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The SLC2A5 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
GLUT5(Glucose transporter 5), also known as SLC2A5, is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The GLUT5 gene is located on chromosome 1. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient. In humans the GLUT5 protein is encoded by the SLC2A5 gene.
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Related articles
1. Burant, C. F., Takeda, J., Brot-Laroche, E., Bell, G. I., Davidson, N. O.Fructose transporter in human spermatozoa and small intestine is GLUT5.J. Biol. Chem. 267: 14523-14526, 1992. 2. Davidson, N. O., Hausman, A. M. L., Ifkovits, C. A., Buse, J. B., Gould, G. W., Burant, C. F., Bell, G. I.Human intestinal glucose transporter expression and localization of GLUT5.Am. J. Physiol. 262: C795-C800, 1992. 3. Kayano, T., Burant, C. F., Fukumoto, H., Gould, G. W., Fan, Y. S., Eddy, R. L., Byers, M. G., Shows, T. B., Seino, S., Bell, G. I.Human facilitative glucose transporters: isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6).J. Biol. Chem. 265: 13276-13282, 1990.
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Gene Name
SLC2A5
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Protein Name
Solute carrier family 2, facilitated glucose transporter member 5
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Gene Full Name
solute carrier family 2(facilitated glucose/fructose transporter), member 5
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Synonyms
Facilitated glucose transporter member 5 antibody|Fructose transporter antibody|glucose transporter like protein 5 antibody|Glucose transporter type 5 antibody|Glucose transporter type 5 small intestine antibody|GLUT 5 antibody|GLUT-5 antibody|GLUT5 antibody|GTR5_HUMAN antibody|SLC 2A5 antibody|SLC2A5 antibody|small intestine antibody|Solute carrier family 2 antibody
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Uniprot ID
Q9WV38
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
