Prokineticin 1 Antibody

• Catalog number
  PB9882
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Prokineticin 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB
• Immunogen
  E. coli-derived mouse Prokineticin 1 recombinant protein (Position: A20-F105). Mouse Prokineticin 1 shares 88.4% and 94.2% amino acid (aa) sequence identity with human and rat Prokineticin 1, respectively.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Prokineticin 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Prokineticin 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Prokineticin-1 is also known as EG-VEGF. The International Radiation Hybrid Mapping Consortium mapped the PROK1 gene to chromosome 1. The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
• Related articles
  1. LeCouter, J., Kowalski, J., Foster, J., Hass, P., Zhang, Z., Dillard-Telm, L., Frantz, G., Rangell, L., DeGuzman, L., Keller, G.-A., Peale, F., Gurney, P., Hillan, K. J., Ferrara, N. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature 412: 877-884, 2001. 2. Li, M., Bullock, C. M., Knauer, D. J., Ehlert, F. J., Zhou, Q. Y. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle. Molec. Pharm. 59: 692-698, 2001.
• Gene Name
  PROK1
• Protein Name
  Prokineticin-1
• Gene Full Name
  prokineticin 1
• Synonyms
  Black mamba toxin related protein antibody|EG VEGF antibody|EG-VEGF antibody|EGVEGF antibody|Endocrine-gland-derived vascular endothelial growth factor antibody|Mambakine antibody|PK1 antibody|PRK1 antibody|PROK1 antibody|PROK1_HUMAN antibody|Prokineticin-1 antibody
• Uniprot ID
  Q14A28
• Entrez GeneID
  246691
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Prokineticin  
• Gene symbol
  PROK1, PROKR1, PROKR2
• Short name
  Prokineticin 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Prokineticin 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18454
• Gene
  PROK1
• Long gene name
  prokineticin 1
• Synonyms
  • PK1
  • PRK1
  • EGVEGF
• Synonyms name
  • black mamba toxin-related protein
  • mambakine
• GenBank acession
  • AF333024
• Locus
  1p13.3
• Discovery year
  2002-07-22
• Entrez gene record
  84432
• Pubmed identfication
  • 11259612
• RefSeq identity
  • NM_032414
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000011569

Gene info

• Identity
  HGNC:4524
• Gene
  PROKR1
• Long gene name
  prokineticin receptor 1
• Synonyms gene
  • GPR73
• Synonyms gene name
  • G protein-coupled receptor 73
• Synonyms
  • PKR1
  • ZAQ
  • GPR73a
• GenBank acession
  • AF506287
• Locus
  2p13.3
• Discovery year
  1999-07-30
• Entrez gene record
  10887
• Pubmed identfication
  • 10760605
• Classification
  • Prokineticin receptors
• VEGA ID
  OTTHUMG00000129567

Gene info

• Identity
  HGNC:15836
• Gene
  PROKR2
• Long gene name
  prokineticin receptor 2
• Synonyms gene
  • GPR73L1
  • KAL3
• Synonyms gene name
  • G protein-coupled receptor 73-like 1
  • Kallmann syndrome 3 (autosomal dominant)
• Synonyms
  • GPR73b
  • PKR2
  • GPRg2
  • dJ680N4.3
• GenBank acession
  • AL121755
• Locus
  20p12.3
• Discovery year
  2001-09-17
• Entrez gene record
  128674
• Pubmed identfication
  • 11886876
  • 17054399
• RefSeq identity
  • NM_144773
• Classification
  • Prokineticin receptors
• VEGA ID
  OTTHUMG00000031800

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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