beta Defensin 1 Antibody

• Catalog number
  PA1450
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  beta Defensin 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  rat Predicted to work with: mouse
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1(52-68aa FTKIQGTCYRGKAKCCK).
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the beta Defensin 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The beta Defensin 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
• Related articles
  1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J. 2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. 3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin.
• Gene Name
  DEFB1
• Protein Name
  Beta-defensin 1(BD-1/hBD-1)
• Gene Full Name
  defensin, beta 1
• Synonyms
  BD 1 antibody|BD-1 antibody|BD1 antibody|beta 1 antibody|Beta defensin 1 antibody|Beta-defensin 1 antibody|DEFB 1 antibody|DEFB1 antibody|DEFB1_HUMAN antibody|DEFB101 antibody|Defensin antibody|Defensin beta 1 antibody|Defensin beta 1 preproprotein antibody|HBD 1 antibody|hBD-1 antibody|HBD1 antibody|MGC51822 antibody
• Uniprot ID
  P60022
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
• French translation
  anticorps

• Gene target
  beta   Defensin  
• Gene symbol
  DEFB1, DEFB108A, DEFB109A
• Short name
  beta Defensin 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  b Defensin 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2766
• Gene
  DEFB1
• Long gene name
  defensin beta 1
• Synonyms gene name
  • defensin, beta 1
• Synonyms
  • HBD-1
  • DEFB-1
  • DEFB101
  • HBD1
  • BD1
  • MGC51822
• Synonyms name
  • beta-defensin 1
  • beta defensin 1
• GenBank acession
  • X92744
• Locus
  8p23.1
• Discovery year
  1997-05-29
• Entrez gene record
  1672
• Pubmed identfication
  • 7628632
• RefSeq identity
  • NM_005218
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000090367

Gene info

• Identity
  HGNC:18089
• Gene
  DEFB108A
• Long gene name
  defensin beta 108A
• Synonyms gene
  • DEFB108
  • DEFB108P1
• Synonyms gene name
  • defensin, beta 108
  • defensin, beta 108, pseudogene 1
  • defensin beta 108 pseudogene 1
• Synonyms
  • DEFB-8
• Locus
  8p23.1
• Discovery year
  2002-05-09
• Entrez gene record
  503694
• Pubmed identfication
  • 11854508
• RefSeq identity
  • NG_005426
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000165402

Gene info

• Identity
  HGNC:18090
• Gene
  DEFB109A
• Long gene name
  defensin beta 109A (pseudogene)
• Synonyms gene
  • DEFB109
  • DEFB109P1
• Synonyms gene name
  • defensin, beta 109
  • defensin, beta 109, pseudogene 1
  • defensin beta 109 pseudogene 1
• Synonyms
  • DEFB-9
• Locus
  8p23.1
• Discovery year
  2002-05-09
• Entrez gene record
  245912
• Pubmed identfication
  • 11854508
• RefSeq identity
  • NR_024044
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000158671

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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