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Target antigen
alpha Lactalbumin
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human
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Analyses
WB,IHC-P
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Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human alpha Lactalbumin(20-37aa KQFTKCELSQLLKDIDGY).
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the alpha Lactalbumin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The alpha Lactalbumin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
LALBA(lactalbumin, alpha or alpha-lactalbumin) is a protein that in humans is encoded by the LALBA gene. The LALBA gene is mapped on 12q13.11. alpha-Lactalbumin is an important whey protein in cow's milk(1 g/l), and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. alpha-Lactalbumin forms the regulatory subunit of the lactose synthase(LS) heterodimer and beta-1, 4-galactosyltransferase(beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a multimer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of human alpha-lactalbumin that may form in acidic environments such as the stomach, called HAMLET, probably induces apoptosis in tumor and immature cells.
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Related articles
1. Bounous, G., Kongshavn, P. A. L., Taveroff, A., Gold, P. Evolutionary traits in human milk proteins. Med. Hypotheses 27: 133-140, 1988. 2. Davies, M. S., West, L. F., Davis, M. B., Povey, S., Craig, R. K. The gene for human alpha-lactalbumin is assigned to chromosome 12q13. Ann. Hum. Genet. 51: 183-188, 1987. 3. Hakansson, A., Zhivotovsky, B., Orrenius, S., Sabharwal, H., Svanborg, C. Apoptosis induced by a human milk protein. Proc. Nat. Acad. Sci. 92: 8064-8068, 1995.
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Gene Name
LALBA
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Protein Name
Alpha-lactalbumin
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Gene Full Name
lactalbumin, alpha-
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Synonyms
a-LACTA antibody|alfaLA antibody|Alpha-lactalbumin antibody|Lactalbumin alpha antibody|Lactose synthase B protein antibody|LALBA antibody|LALBA_HUMAN antibody|Lysozyme-like protein 7 antibody|LYZL7 antibody|MGC138521 antibody|MGC138523 antibody
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Uniprot ID
P00709
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Description
The alpha Lactalbumin Antibody is a α- or alpha protein sometimes glycoprotein present in blood.
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
