Adenylate Kinase 1 Antibody
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Catalog numberPB10033
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PricePlease ask
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Size0,1 mg
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Target antigenAdenylate Kinase 1
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman, mouse, rat
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AnalysesWB
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ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human Adenylate Kinase 1 (149-189aa RLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVF SQVCTH), different from the related mouse sequence by seven amino acids, and from the related rat sequence by four amino acids.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the Adenylate Kinase 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe Adenylate Kinase 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundThis gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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Related articles1. Bianchi, P., Zappa, M., Bredi, E., Vercellati, C., Pelissero, G., Barraco, F., Zanella, A. A case of complete adenylate kinase deficiency due to a nonsense mutation in AK-1 gene (arg107-to-stop, CGA-to-TGA) associated with chronic haemolytic anaemia. Brit. J. Haemat. 105: 75-79, 1999. 2. Qualtieri, A., Pedace, V., Bisconte, M. G., Bria, M., Gulino, B., Andreoli, V., Brancati, C. Severe erythrocyte adenylate kinase deficiency due to homozygous A-to-G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemia. Brit. J. Haemat. 99: 770-776, 1997.
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Gene NameAK1
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Protein NameAdenylate kinase isoenzyme 1
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Gene Full Nameadenylate kinase 1
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SynonymsAdenylate kinase 1 | AK 1 | AK1 | ATP-AMP transphosphorylase 1 | KAD1 | Myokinase | P00568
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Uniprot IDP00568
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Entrez GeneID203
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolAK3, AK4, AK4P1
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Short nameAdenylate Kinase 1 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAdenylate phosphorylation catalyst 1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameadenylate kinase 3
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Synonyms gene
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Synonyms gene name
- adenylate kinase 6
- adenylate kinase 3 like 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Adenylate kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameadenylate kinase 4
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Synonyms gene
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Synonyms gene name
- adenylate kinase 3
- adenylate kinase 3-like 1
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Adenylate kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameadenylate kinase 4 pseudogene 1
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Synonyms gene
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Synonyms gene name
- adenylate kinase 3 pseudogene 1
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GenBank acession
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Locus
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Discovery year1992-06-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data