Zanamivir

  • Catalog number
    B1900-10
  • Price
    Please ask
  • Size
    10 mg
  • Alternative_name
    (2R,3R,4S)-3-acetamido-4-(diaminomethylideneamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
  • Description
    Zanamivir is a potent and selective inhibitor of influenza A and B virus neuraminidases with IC₅₀ values of 0.95 nM and 2.7 nM, respectively. It interacts with a group of amino acids in the active site of neuraminidase, that are conserved in all influenza A and B strains. Zanamivir blocks the action of neuraminidase, which blocks the cleavage of sialic acid on the cell receptors, thus preventing release and spread of the newly formed virions.
  • CAS Number
    139110-80-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₂H₂₀N₄O7
  • Molecular Weight
    332.31
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective inhibitor of influenza A and B virus neuraminidases
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00866966
  • PubChem CID
    60855
  • SMILES
    CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N
  • InChi
    InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
  • InChi Key
    ARAIBEBZBOPLMB-UFGQHTETSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Zanamivir
  • Alternative name
    Zanamivir
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