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Alternative_name
1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
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Description
XY1 is an inactive control of SGC707. SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM. XY1 is an analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.
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CAS Number
1624117-53-8
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Structure Available
True
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Salt Form
false
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Molecular Formula
C₁₇H₁₉N₃O₂
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Molecular Weight
297.35
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Cell Permeable
True
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Purity
≥98%
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Solubilities
~10 mg/ml in DMF in 0, ~25 mg/ml in in DMSO
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
An inactive control of SGC707
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Storage Condition
-20ºC
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Shipping Condition
RT
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Shelf Life
36 months
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PubChem CID
78871801
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SMILES
C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2
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InChi
InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22)
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InChi Key
GSQHGSRPQHBTTP-UHFFFAOYSA-N
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MSDS Available
True