Valacyclovir Hydrochloride Hydrate

  • Catalog number
    2201-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    L-Valine 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxy)ethyl Ester Hydrochloride hydrate; valaciclovir
  • Description
    Valacyclovir is a prodrug of Acyclovir (Cat.No. 2200-50, 250) with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain.
  • CAS Number
    124832-27-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₃H₂₀N₆O₄·HCl·xH2O
  • Molecular Weight
    360.80 (anhydrous basis)
  • Cell Permeable
    Yes
  • Purity
    ≥97% by HPLC
  • Solubilities
    H₂O (>20 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    An antiviral agent
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD01861507
  • PubChem CID
    60772
  • SMILES
    CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl
  • InChi
    InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
  • InChi Key
    ZCDDBUOENGJMLV-QRPNPIFTSA-N
  • MSDS Available
    Yes
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