SSR-240612

  • Catalog number
    B2349-5
  • Price
    410.55 USD
  • Size
    5 mg
  • Alternative_name
    (3R)-3-(1,3-benzodioxol-5-yl)-N-[(6-methoxy-2-naphthalenyl)sulfonyl]-β-alanyl-4-[[(2R,6S)-2,6-dimethyl-1-piperidinyl]methyl]-N-methyl-N-(1-methylethyl)-D-phenylalaninamide, monohydrochloride
  • Description
    SSR-240612 is a potent and selective, non-peptide antagonist of the bradykinin B1 receptor (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively). It inhibits the contraction of rabbit aorta and rat ileum induced by the B1 receptor agonist des-Arg9-bradykinin (des-Arg9-BK) ex vivo in a concentration-dependent manner.
  • CAS Number
    464930-42-5
  • Structure Available
    Yes
  • Molecular Formula
    C₄₂H₅₂N₄O₇S • HCl
  • Molecular Weight
    793.4
  • Cell Permeable
    1
  • Purity
    ≥98% by HPLC
  • Solubilities
    >25 mg/ml (DMSO) in 0
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A potent, and specific non-peptide bradykinin B1 receptor antagonist
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    44235958
  • SMILES
    CC1CCCC(N1CC2=CC=C(C=C2)CC(C(=O)N(C)C(C)C)NC(=O)CC(C3=CC4=C(C=C3)OCO4)NS(=O)(=O)C5=CC6=C(C=C5)C=C(C=C6)OC)C.Cl
  • InChi
    InChI=1S/C42H52N4O7S.ClH/c1-27(2)45(5)42(48)38(20-30-10-12-31(13-11-30)25-46-28(3)8-7-9-29(46)4)43-41(47)24-37(34-16-19-39-40(23-34)53-26-52-39)44-54(49,50)36-18-15-32-21-35(51-6)17-14-33(32)22-36;/h10-19,21-23,27-29,37-38,44H,7-9,20,24-26H2,1-6H3,(H,43,47);1H/t28-,29+,37-,38-;/m1./s1
  • InChi Key
    GLHHFOSVBQQNAW-GDYXXZBVSA-N
  • MSDS Available
    1
  • Gene target
  • Short name
    SSR-240612
  • Alternative name
    SSR-240612
Similar products
Filters
Contact
Chat with gentaur.com employee