Ruxolitinib phosphate

• Catalog number
  B2631-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  INCB-018424 (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate INC-424 INCB018424
• Description
  Ruxolitinib phosphate is the phosphate salt form of ruxolitinib, a potent Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation.
• CAS Number
  1092939-17-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₂₁N₆O₄P
• Molecular Weight
  404.37
• Cell Permeable
  True
• Purity
  ≥98% by HPLC
• Solubilities
  >30 mg/ml in DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A potent Janus Kinase (JAK) inhibitor
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  25127112
• PubChem CID Link
• SMILES
  N#CC[C@@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4.O=P(O)(O)O
• InChi
  InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1
• InChi Key
  JFMWPOCYMYGEDM-XFULWGLBSA-N
• Data Sheet Link
• MSDS Available
  True

• Gene target
  Ruxolitinib   phosphate  
• Short name
  Ruxolitinib phosphate
• Alternative name
  Ruxolitinib phosphate

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