Retro-2

• Catalog number
  2516-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  Retro-2(cycl); (±)-2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one; Ricin retrograde transport blocker
• Description
  An inhibitor of ribosome-inactivating proteins (RIPs). At a concentration of 200 mg/kg, Retro-2 displayed full protection of mice against a dose of ricin that killed 90% of an unprotected control mouse population. Blocks Leishmania parasitophorous vacuole (LPV) development. Retro-2 inhibited the replication of Leishmania parasites in axenic cultures.
• CAS Number
  1429192-00-6
• Structure Available
  Yes
• Peptide sequence
  No
• Salt Form
  No
• Molecular Formula
  C₁₉H₁₆N₂OS
• Molecular Weight
  320.41
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  Inhibitor of Ribosome-Inactivating Proteins (RIPs)
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  24 months
• SMILES
  O=C1N(C2=CC=CC=C2)C(C3=CC=C(C)S3)NC4=C1C=CC=C4
• InChi
  InChI=1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3
• InChi Key
  BOAPXDSRULBILC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Retro-2  
• Short name
  Retro-2
• Alternative name
  Retro-2
• Virus
  retro

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