Prostaglandin E2

• Catalog number
  2268-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  9-​Oxo-​11α,​15S-​dihydroxy-​prosta-​5Z,​13E-​dien-​1-​oic acid; PGE2; Dinoprostone
• Description
  Prostaglandin E2 (PGE2) is a primary product of arachidonic metabolism and is synthesized via the cyclooxygenase (COX) and prostaglandin synthase pathways. PGE2 production is a commonly used method for the detection of COX-1 and COX-2 modulation and prostaglandin synthases. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Regulates vertebrate haematopoietic stem cell homeostasis.
• CAS Number
  363-24-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₃₂O₅
• Molecular Weight
  352.47
• Cell Permeable
  No
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (~100 mg/ml) or EtOH (~100 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An endogenous prostanoid
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00077861
• PubChem CID
  5280360
• PubChem CID Link
• SMILES
  CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
• InChi
  InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1
• InChi Key
  XEYBRNLFEZDVAW-ARSRFYASSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Prostaglandin  
• Short name
  Prostaglandin E2
• Alternative name
  Prostaglandin E2

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