PP1

  • Catalog number
    1927-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • Description
    Cell-permeable. A potent Src-selective tyrosine kinase (TK) inhibitor. Inhibits p56lck and p59fynT (IC₅₀ values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also inhibits Kit and Bcr-Abl tyrosine kinases.
  • CAS Number
    172889-26-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₆H₁₉N₅
  • Molecular Weight
    281.36
  • Cell Permeable
    Yes
  • Purity
    ≥98% by TLC
  • Solubilities
    DMSO (25 mg/ml) or Ethanol (10 mg/ml)
  • Handling
    Protect from light and air
  • Tag Line
    A potent Src-selective tyrosine kinase (TK) inhibitor.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD01076570
  • PubChem CID
    1400
  • SMILES
    CC1=CC=C(C=C1)C2=NN(C3=C2C(=NC=N3)N)C(C)(C)C
  • InChi
    InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)
  • InChi Key
    ZVPDNRVYHLRXLX-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    PP1  
  • Gene symbol
    NPY4R, PPA1
  • Short name
    PP1
  • Alternative name
    PP1
Gene info
Gene info
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