PP1
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Catalog number1927-1
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PricePlease ask
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Size1 mg
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Alternative_name1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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DescriptionCell-permeable. A potent Src-selective tyrosine kinase (TK) inhibitor. Inhibits p56lck and p59fynT (IC₅₀ values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also inhibits Kit and Bcr-Abl tyrosine kinases.
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CAS Number172889-26-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₆H₁₉N₅
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Molecular Weight281.36
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Cell PermeableYes
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Purity≥98% by TLC
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SolubilitiesDMSO (25 mg/ml) or Ethanol (10 mg/ml)
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HandlingProtect from light and air
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Tag LineA potent Src-selective tyrosine kinase (TK) inhibitor.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD01076570
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PubChem CID1400
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SMILESCC1=CC=C(C=C1)C2=NN(C3=C2C(=NC=N3)N)C(C)(C)C
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InChiInChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)
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InChi KeyZVPDNRVYHLRXLX-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolNPY4R, PPA1
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Short namePP1
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Alternative namePP1
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Gene info
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Identity
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Gene
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Long gene nameneuropeptide Y receptor Y4
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Synonyms gene
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Synonyms gene name
- pancreatic polypeptide receptor 1
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Synonyms
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Locus
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Discovery year1996-04-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Neuropeptide Y receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinorganic pyrophosphatase 1
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Synonyms gene
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Synonyms gene name
- pyrophosphatase (inorganic)
- pyrophosphatase (inorganic) 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID