PCI 34051

• Catalog number
  2251-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-​hydroxy-​1-​[(4-​methoxyphenyl)methyl]-​1H-​indole-​6-​carboxamide
• Description
  PCI 34051 is a potent histone deacetylase 8 (HDAC8) inhibitor (IC₅₀ = 0.01 μM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC₅₀s = 4, >50, >50, 2.9, and 13 μM, respectively).
• CAS Number
  950762-95-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₆N₂O₃
• Molecular Weight
  296.32
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  A potent HDAC8 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD11114393
• PubChem CID
  24753719
• PubChem CID Link
• SMILES
  COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
• InChi
  InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)
• InChi Key
  AJRGHIGYPXNABY-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PCI   34051  
• Gene symbol
  SERPINA5
• Short name
  PCI 34051
• Alternative name
  PCI 34051

Gene info

• Identity
  HGNC:8723
• Gene
  SERPINA5
• Long gene name
  serpin family A member 5
• Synonyms gene
  • PLANH3
  • PCI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
• Synonyms
  • PAI3
  • PROCI
• Synonyms name
  • Protein C inhibitor
• GenBank acession
  • M68516
• Locus
  14q32.13
• Discovery year
  1992-10-02
• Entrez gene record
  5104
• Pubmed identfication
  • 1714450
  • 8381582
  • 24172014
• RefSeq identity
  • NM_000624
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000170860
• Locus Specific Databases
  • LRG_644

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