MS-275 (Entinostat, SNDX-275)

  • Catalog number
    1590-5
  • Price
    1026.93 USD
  • Size
    5 mg
  • Alternative_name
    Entinostat, SNDX-276
  • Description
    Preferentially inhibits HDAC1 (IC₅₀ = 300 nM) over HDAC3 (IC₅₀ = 8 µM). Has no inhibitory activity towards HDAC8 (IC₅₀>100 µM).
  • CAS Number
    209783-80-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₁H₂₀N₄O₃
  • Molecular Weight
    376.41
  • Cell Permeable
    Yes
  • Purity
    ≥99% by HPLC
  • Solubilities
    DMSO (38 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    A HDAC1 and HDAC3 inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    RT
  • Shelf Life
    24months
  • MDL Number
    MFCD08272435
  • PubChem CID
    4261
  • SMILES
    C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
  • InChi
    InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13- 24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
  • InChi Key
    INVTYAOGFAGBOE-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    MS-275 (Entinostat, SNDX-275)
  • Alternative name
    MS-275 (Entinostat, SNDX-275)
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