MHY1485
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Catalog number9419-5
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PricePlease ask
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Size5 mg
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Alternative_name4,6-Dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
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DescriptionMHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this inhibitory effect is clearly confirmed in cells under starvation, a strong physiological inducer of autophagy.
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CAS Number326914-06-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₂₁N₇O₄
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Molecular Weight387.39
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~ 2 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent mTOR activator
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID2834965
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SMILESC1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCOCC4
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InChiInChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H,5-12H2,(H,18,19,20,21)
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InChi KeyMSSXBKQZZINCRI-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameMHY1485
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Alternative nameMHY1485
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