IOX1

• Catalog number
  2266-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  8-Hydroxy-5-quinolinecarboxylic acid; 8-Hydroxy-5-quinolinecarboxylic acid
• Description
  Cell-permeable. A histone demethylase (HDM) JMJD nhibitor. Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC₅₀s = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 µM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling.
• CAS Number
  5852-78-8
• Structure Available
  Yes
• Peptide sequence
  No
• Salt Form
  No
• Molecular Formula
  C₁₀H₇NO₃
• Molecular Weight
  189.17
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  Histone demethylase JMJD inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD18417145
• PubChem CID
  459617
• PubChem CID Link
• SMILES
  C1=CC2=C(C=CC(=C2N=C1)O)C(=O)O
• InChi
  InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
• InChi Key
  JGRPKOGHYBAVMW-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  IOX1  
• Short name
  IOX1
• Alternative name
  IOX1

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