Human CellExp™ FGL1, Fc Tag, Cynomolgus / Rhesus macaque recombinant

• Catalog number
  P1418-10
• Price
  Please ask
• Size
  10 µg

• Synonyms
  FGL1, Hepassocin, HP-041, HFREP-1, LFIRE-1, HFREP1
• Alternative_names
  FGL1, Hepassocin, HP-041, HFREP-1, LFIRE-1, HFREP1
• Description
  a novel targets for radiation-induced lung fibrosis
• Recombinant
  False
• Source
  HEK 293 cells
• Purity by SDS PAGE
  >95%
• Assay
  SDS-PAGE
• Endotoxin Level
  Less than 1.0 EU per ug by the LAL method.
• Activity Specifications test method
  Immobilized Human LAG-3, mouse IgG2a Fc tag at 5 ug/ml (100 ul/well) can bind Cynomolgus / Rhesus macaque FGL1, Fc Tag with a linear range of 8-125 ng/ml.
• Molecular Weight
  This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.4 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Sterile Filtered colorless solution
• Reconstitution Instructions
  Reconstitute in sterile deionized water to the desired protein concentration.
• Background Information
  Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.
• Amino acid sequence
  AA Leu 23 - Ile 312
• Handling
  Centrifuge the vial prior to opening.
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants
• About
  Monkeys like rhesus's or the rhesus macaque (Macaca mulatta) are the most used apes in laboraty models.

• Gene target
  CellExp™   FGL1   Tag   Cynomolgus   macaque  
• Gene symbol
  FGL1
• Short name
  CellExp™ FGL1, Fc Tag, Cynomolgus / macaque recombinant
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  Fc Tag
• Species
  Humans, Rhesuses
• Alternative name
  H. sapiens CellExp™ FGL1, fragment c detection labelled, Cynomolgus / Rhesus macaque Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:3695
• Gene
  FGL1
• Long gene name
  fibrinogen like 1
• Synonyms
  • HFREP-1
  • HPS
• Synonyms name
  • hepassocin
• GenBank acession
  • D14446
• Locus
  8p22
• Discovery year
  1995-05-25
• Entrez gene record
  2267
• Pubmed identfication
  • 8390249
• RefSeq identity
  • NM_004467
• Classification
  • Fibrinogen C domain containing
• VEGA ID
  OTTHUMG00000096989

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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