GSK2330672

  • Catalog number
    B1102-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    3-({[(3R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,4-benzothiazepin-8-yl]methyl}amino)pentanedioic acid
  • Description
    GSK2330672 is a highly selective, potent, nonabsorbable ASBT(Apical Sodium dependent bile acid transporter) inhibitor (IC₅₀ = 42 nM). It lowers glucose in an animal model of type 2 diabetes.
  • CAS Number
    1345982-69-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₈H₃₈N₂O₇S
  • Molecular Weight
    546.68
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>20 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A highly selective and potent ASBT (Apical Sodium dependent bile acid transporter) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    53492727
  • SMILES
    CCCCC1(CS(=O)(=O)C2=CC(=C(C=C2C(N1)C3=CC=CC=C3)OC)CNC(CC(=O)O)CC(=O)O)CC
  • InChi
    InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15-26(33)34)23(37-3)16-22(24)27(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27,29-30H,4-6,12,14-15,17-18H2,1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1
  • InChi Key
    CZGVOBIGEBDYTP-VSGBNLITSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    GSK2330672
  • Alternative name
    GSK2330672
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