GSK2330672
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Catalog numberB1102-1
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PricePlease ask
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Size1 mg
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Alternative_name3-({[(3R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,4-benzothiazepin-8-yl]methyl}amino)pentanedioic acid
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DescriptionGSK2330672 is a highly selective, potent, nonabsorbable ASBT(Apical Sodium dependent bile acid transporter) inhibitor (IC₅₀ = 42 nM). It lowers glucose in an animal model of type 2 diabetes.
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CAS Number1345982-69-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₈H₃₈N₂O₇S
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Molecular Weight546.68
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>20 mg/ml)
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HandlingProtect from air and light
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Tag LineA highly selective and potent ASBT (Apical Sodium dependent bile acid transporter) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID53492727
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SMILESCCCCC1(CS(=O)(=O)C2=CC(=C(C=C2C(N1)C3=CC=CC=C3)OC)CNC(CC(=O)O)CC(=O)O)CC
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InChiInChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15-26(33)34)23(37-3)16-22(24)27(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27,29-30H,4-6,12,14-15,17-18H2,1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1
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InChi KeyCZGVOBIGEBDYTP-VSGBNLITSA-N
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MSDS AvailableYes
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Gene target
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Short nameGSK2330672
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Alternative nameGSK2330672
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