Gilteritinib

  • Catalog number
    B1294-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; ASP 2215
  • Description
    Gilteritinib is a potent FLT3 (FMS-like tyrosine kinase 3) inhibitor which shows potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.
  • CAS Number
    1254053-43-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₉H₄₄N₈O₃
  • Molecular Weight
    552.71
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent FLT3 (FMS-like tyrosine kinase 3) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    49803313
  • SMILES
    CCC1=NC(=C(N=C1NC2CCOCC2)NC3=CC(=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC)C(=O)N
  • InChi
    InChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34)
  • InChi Key
    GYQYAJJFPNQOOW-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Gilteritinib
  • Alternative name
    Gilteritinib
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