Gilteritinib
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Catalog numberB1294-25
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PricePlease ask
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Size25 mg
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Alternative_name6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; ASP 2215
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DescriptionGilteritinib is a potent FLT3 (FMS-like tyrosine kinase 3) inhibitor which shows potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.
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CAS Number1254053-43-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₉H₄₄N₈O₃
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Molecular Weight552.71
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent FLT3 (FMS-like tyrosine kinase 3) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID49803313
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SMILESCCC1=NC(=C(N=C1NC2CCOCC2)NC3=CC(=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC)C(=O)N
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InChiInChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34)
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InChi KeyGYQYAJJFPNQOOW-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameGilteritinib
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Alternative nameGilteritinib
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