Fumagillin

• Catalog number
  2368-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  Amebacilin; Fugilin; Fumidil; Fumadil B; NSC9168; U5762
• Description
  Fumagillin is a meroterpenoid antibiotic isolated from Aspergillus fumigatus. An anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo.
• CAS Number
  23110-15-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₃₄O₇
• Molecular Weight
  458.54
• Cell Permeable
  Yes
• Purity
  ≥98% by NMR
• Solubilities
  Ethanol (~ 1 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  An angiogenesis inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD03990453
• PubChem CID
  6917655
• PubChem CID Link
• SMILES
  CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C
• InChi
  InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3, 33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1
• InChi Key
  NGGMYCMLYOUNGM-CSDLUJIJSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fumagillin  
• Short name
  Fumagillin
• Alternative name
  Fumagillin

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