EZBlock™ Protease Inhibitor Cocktail VIII, DMSO-Free

• Catalog number
  K395-1
• Price
  Please ask
• Size
  1 vial

• Description
  A cocktail of five protease inhibitors with broad specificity for the inhibition of aspartic, serine, cysteine, aminopeptidases and thermolysin-like proteases. This cocktail is recommended for purification of proteins containing His-Tag sequences. One ml of the reconstituted cocktail is recommended for about 10 g of cells. Each vial contains 100 mM of AEBSF, HCl (Cat. No.1644), 5 mM of Bestatin (Cat. No. 1733), 1.5 mM of E-64 (Cat. No 1739), 2 mM of Pepstatin A (Cat. No. 1732) and 200 µM of Phosphoramidon disodium salt.
• Salt Form
  No
• Cell Permeable
  No
• Handling
  Protect from air and moisture
• Tag Line
  A Protease inhibitor cocktail
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• SMILES
  N/A
• InChi
  N/A
• InChi Key
  N/A
• Data Sheet Link
• MSDS Available
  Yes
• Test
  This inhibitor of proteases will block aspartic protease, cysteine protease, serine proteases, metalloproteases and aminopeptidases. Lyophilized, EDTA free.
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Protease   Inhibitor   Cocktail   VIII   DMSO-Free  
• Gene symbol
  COX8A, G3BP1, MARCHF8
• Short name
  EZBlock™ Protease Inhibitor Cocktail VIII, DMSO-Free
• Technique
  Ezblock, ezblocks
• Alternative name
  EZBlock™ Protease suppressor Cocktail VIII, DMSO-Free
• Alternative technique
  blocks

Gene info

• Identity
  HGNC:2294
• Gene
  COX8A
• Long gene name
  cytochrome c oxidase subunit 8A
• Synonyms gene
  • COX8
• Synonyms gene name
  • cytochrome c oxidase subunit VIII
  • cytochrome c oxidase subunit VIIIA (ubiquitous)
• Synonyms
  • COX8-2
  • COX8L
  • VIII-L
  • COX
  • VIII
• GenBank acession
  • J04823
• Locus
  11q13.1
• Discovery year
  1989-06-30
• Entrez gene record
  1351
• Pubmed identfication
  • 2543673
  • 2847943
  • 26685157
• RefSeq identity
  • NM_004074
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000167785

Gene info

• Identity
  HGNC:30292
• Gene
  G3BP1
• Long gene name
  G3BP stress granule assembly factor 1
• Synonyms gene name
  • GTPase activating protein (SH3 domain) binding protein 1
• Synonyms
  • HDH-VIII
  • G3BP
• Synonyms name
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • DNA helicase VIII
• GenBank acession
  • BC006997
• Locus
  5q33.1
• Discovery year
  2006-10-25
• Entrez gene record
  10146
• Pubmed identfication
  • 8649363
  • 9889278
  • 25229650
• RefSeq identity
  • NM_005754
• Classification
  • RNA binding motif containing
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000130123

Gene info

• Identity
  HGNC:23356
• Gene
  MARCHF8
• Long gene name
  membrane associated ring-CH-type finger 8
• Synonyms gene
  • MIR
  • MARCH8
• Synonyms gene name
  • c-mir, cellular modulator of immune recognition
  • membrane-associated ring finger (C3HC4) 8
  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
• Synonyms
  • c-MIR
  • CMIR
  • MARCH-VIII
  • RNF178
• GenBank acession
  • AL833316
• Locus
  10q11.21-q11.22
• Discovery year
  2003-11-12
• Entrez gene record
  220972
• Pubmed identfication
  • 12582153
  • 14722266
• RefSeq identity
  • NM_145021
• Classification
  • Ring finger proteins
  • Membrane associated ring-CH-type fingers
• VEGA ID
  OTTHUMG00000019345

Similar products