Evobrutinib
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Catalog numberB2379-5
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PricePlease ask
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Size5 mg
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Alternative_name, 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)prop-2-en-1-one, MSC-2364447C, M-2951
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DescriptionEvobrutinib is a potent and selective Bruton’s tyrosine kinase (BTK) inhibitor potentially useful for the treatment of autoimmune diseases.
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CAS Number1415823-73-2
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Structure AvailableYes
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Molecular FormulaC₂₅H₂₇N₅O₂
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Molecular Weight429.52
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Cell Permeable1
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Purity≥98% by HPLC
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Solubilities~5 mg/ml in DMSO
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineA highly selective Bruton’s tyrosine kinase (BTK) inhibitor
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID71479709
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SMILESC=CC(=O)N1CCC(CC1)CNC2=NC=NC(=C2C3=CC=C(C=C3)OC4=CC=CC=C4)N
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InChiInChI=1S/C25H27N5O2/c1-2-22(31)30-14-12-18(13-15-30)16-27-25-23(24(26)28-17-29-25)19-8-10-21(11-9-19)32-20-6-4-3-5-7-20/h2-11,17-18H,1,12-16H2,(H3,26,27,28,29)
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InChi KeyQUIWHXQETADMGN-UHFFFAOYSA-N
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MSDS Available1
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Gene target
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Short nameEvobrutinib
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Alternative nameEvobrutinib
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