(-)-Equol

• Catalog number
  B3081-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol; (S)-Equol; 4',7-Isoflavandiol; 4',7-Dihydroxyisoflavan; (S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
• Description
  S-equol is a metabolite of soy isoflavonoid phytoestrogen daidzein, produced by human intestinal bacteria. S-equol has a high affinity for estrogen receptor beta (ERβ) than estrogen receptor (ERα) with Ki values of 0.73 and 6.4 nM respectively. It inhibits the growth of LnCaP, DU145 and PC3 human prostate cancer cell lines. It has significant anti-prostate cancer activities in vitro and in vivo. The anticancer effects are associated with the activation of FOXO3a via an Akt-specific pathway and inhibitory effects on MDM2 expression.
• CAS Number
  531-95-3
• Structure Available
  1
• Molecular Formula
  C₁₅H₁₄O₃
• Molecular Weight
  242.27
• Cell Permeable
  1
• Purity
  ≥ 98%
• Solubilities
  ~15 mg/ml in DMSO, DMF or ethanol
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A high affinity agonist for ERβ
• Storage Condition
  -20ºC
• Shipping Condition
  RT
• Shelf Life
  36 months
• MDL Number
  MFCD00200962
• PubChem CID
  91469
• PubChem CID Link
• SMILES
  C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
• InChi
  InChI=1S/C15H14O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-6,8,12,16-17H,7,9H2/t12-/m1/s1
• InChi Key
  ADFCQWZHKCXPAJ-GFCCVEGCSA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Equol  
• Short name
  (-)-Equol
• Alternative name
  (-)-Equol

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